样本编号 | SAMC1841225 |
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外部数据库编号 | GSA-Human: HRS276280 |
样品名称 | Pt#4(R) |
样本标题 | Pt#4(R) |
样品类型 | Human sample |
物种名称 | Homo sapiens |
描述信息 | RR_AML |
样本属性 | *该样本包含更多受控访问信息,请通过GSA-Human系统申请项目HRA001240数据获取。 |
发布日期 | 2022-10-25 |
项目编号 | PRJCA005787 |
提交者 | Wang Qianghu (wangqh@njmu.edu.cn) |
提交单位 | Nanjing Medical University |
提交日期 | 2023-06-18 |
资源名称 | 描述 |
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GSA-Human (1) | - |
HRA001240 (Controlled Access) | Chemoresistance and relapse are the leading cause of poor outcomes for patients with acute myeloid leukemia (AML). The high intratumoral heterogeneity (ITH) and the co-evolution between leukemia cells and the microenvironment are the main reasons for drug resistance. Utilizing single-cell RNA sequencing (scRNA-seq), we dissect the cellular states and the immune microenvironment of bone marrow from primary refractory or short-term relapsed AML patients. |