| HRA005298
(Controlled Access)
|
Heart failure (HF) seriously threatens human's health world widely. However, the pathological mechanisms of HF are still not fully clear. In this study, we performed proteomics and transcriptomics analysis to overview the detailed changes of proteins and mRNAs in HF with human heart failure samples and healthy donors, and found there was a great difference in the protein change pattern between the atrium and ventricle of HF myocardium. It is interested that metabolism model changed in ventricular tissue of HF samples, and inflammation pathways were activated in atrial tissues. Through analysis of the differentially expressed genes in the heart failure samples. |
