样本编号	SAMC3457110
外部数据库编号	GSA-Human: HRS1189502
样品名称	H-Exo_2
样本标题	Exosomes_H_2
样品类型	Human sample
物种名称	Homo sapiens
描述信息	Exosomes from MHCC97H cells grown on high-stiffness substrate (16 kPa)
样本属性	*该样本包含更多受控访问信息，请通过GSA-Human系统申请项目HRA006931数据获取。
发布日期	2024-12-23
项目编号	PRJCA024399
提交者	Jiefeng Cui (cui.jiefeng@zs-hospital.sh.cn)
提交单位	Zhongshan Hospital, Fudan University
提交日期	2024-03-21

样本包含数据信息

资源名称	描述
GSA-Human (1)	-
HRA006931 (Controlled Access)	Existing clinical studies have indicated that increased matrix stiffness is positively correlated with an unfavorable prognosis of HCC, and liver stiffness has been taken as a biomarker in clinics to predict HCC progress and its outcome. This study aims to explore whether increased matrix stiffness tuned HCC cell-released exosomal miRNAs trigger HCC metastasis. Exosomes were first isolated and purified from CM of MHCC97H cells grown on low (6 kPa) and high-stiffness (16 kPa) substrates. Small RNAs in exosomes were further subjected to sequencing via the Illumina NovaSeq 6000 platform.

资源名称

描述

GSA-Human (1)

HRA006931 (Controlled Access)

Existing clinical studies have indicated that increased matrix stiffness is positively correlated with an unfavorable prognosis of HCC, and liver stiffness has been taken as a biomarker in clinics to predict HCC progress and its outcome. This study aims to explore whether increased matrix stiffness tuned HCC cell-released exosomal miRNAs trigger HCC metastasis. Exosomes were first isolated and purified from CM of MHCC97H cells grown on low (6 kPa) and high-stiffness (16 kPa) substrates. Small RNAs in exosomes were further subjected to sequencing via the Illumina NovaSeq 6000 platform.