样本编号	SAMC3758723
外部数据库编号	GSA-Human: HRS1251423
样品名称	HSCR-01-0081-00
样本标题	HSCR-01-0081-00
样品类型	Human sample
物种名称	Homo sapiens
描述信息	Tumor; Adjacent nonTumor(sample_name:Species-CancerType-DonorID-SampleType; Species(HSCR:Human Single cell RNA, HSTR:Human Spatial Transcriptome RNA); CancerType(01:AM, 02:BCC, 03:BW, 04:CM, 05:CSCC, 06:CSDM, 07:LSCC, 08:LUAD, 09:MM, 10:nCSDM, 11:LSCC, 12:PC, 13:PSCC, XX:multiple cancer, 00:LUNG); SampleType(00:Mixed sampling, 01:Primary Solid Tumor, 02:Lymph Node Metastatic, 03:Solid Tissue Normal, 04:Normal Tissue, 05:Normal Congenital Nevi))
样本属性	*该样本包含更多受控访问信息，请通过GSA-Human系统申请项目HRA007441数据获取。
发布日期	2024-05-24
项目编号	PRJCA018695
提交者	Mingzhu Yin (yinmingzhu2008@126.com)
提交单位	Chongqing University Three Gorges Hospital
提交日期	2024-05-25

样本包含数据信息

资源名称	描述
GSA-Human (1)	-
HRA007441 (Controlled Access)	Tumor growth cannot flourish without the oxygen and nutrients supplied by the blood, making angiogenesis induction one of the most critical cancer hallmarks. In this study, we generated a pan-tumor vasculature atlas by integrating in-house and public single-cell datasets. At the single-cell resolution, we dissected ~200,000 vascular cells, including vascular endothelial cells (ECs), lymphatic ECs (LECs), and mural cells (MCs). Our findings contributed to understanding the tumor angiogenesis processes, LEC lineages, MC phenotypes, and intercellular interactions associated with the tumor vascular microenvironment (TVM). Our comprehensive TVM compilations complemented a missing piece of jigsaw puzzle for the single-cell pan-tumor atlas and provided a reference perspective on tumor vascular normalization and anti-angiogenic therapy.

资源名称

描述

GSA-Human (1)

HRA007441 (Controlled Access)

Tumor growth cannot flourish without the oxygen and nutrients supplied by the blood, making angiogenesis induction one of the most critical cancer hallmarks. In this study, we generated a pan-tumor vasculature atlas by integrating in-house and public single-cell datasets. At the single-cell resolution, we dissected ~200,000 vascular cells, including vascular endothelial cells (ECs), lymphatic ECs (LECs), and mural cells (MCs). Our findings contributed to understanding the tumor angiogenesis processes, LEC lineages, MC phenotypes, and intercellular interactions associated with the tumor vascular microenvironment (TVM). Our comprehensive TVM compilations complemented a missing piece of jigsaw puzzle for the single-cell pan-tumor atlas and provided a reference perspective on tumor vascular normalization and anti-angiogenic therapy.