样本编号 | SAMC3812523 |
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外部数据库编号 | GSA-Human: HRS1285844 |
样品名称 | DNA_4cell_Rep2 |
样本标题 | DNA_4cell_Rep2 |
样品类型 | Human sample |
物种名称 | Homo sapiens |
描述信息 | Human 4-cell embryo |
样本属性 | *该样本包含更多受控访问信息,请通过GSA-Human系统申请项目HRA006264数据获取。 |
发布日期 | 2024-06-24 |
项目编号 | PRJCA022115 |
提交者 | Fan Guo (guofan@ioz.ac.cn) |
提交单位 | Institute of Zoology, Chinese Academy of Sciences |
提交日期 | 2024-06-10 |
资源名称 | 描述 |
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GSA-Human (1) | - |
HRA006264 (Controlled Access) | Epigenetic dysregulation is associated with human infertility and abnormal embryonic development. One important epigenetic modification is DNA 5-hydroxymethylcytosine (5hmC), the conversion of methylcytosine (5mC) to 5hmC by TET enzymes. However, the role of this modification in early human embryos remains largely unknown. Here, we present a single-base-resolution map of 5hmC during human preimplantation development. |