CCAS receives multi-omics data as input for multi-dimensional annotation of tumors. In CCAS, SNV/indels level data is necessary. The data at the Expression, CNV, and Methylation levels are optional. The SNV/indels part accepts data in the form of VCF, MAF, or 5 column table. The Expression, Copy Number Variation (CNV), and Methylation parts receive the genes-value table (Ensembl Gene ID\tValue) as inputs. Meanwhile, CNV and Methylation also support region format (Chr\tStart\tEnd\tValue) as input.