circAtlas 3.0 a gateway to 3 million standardized named vertebrate circular RNAs
Circular RNAs (circRNAs) are a novel class of RNAs with important biological implications. Currently, a large number of circRNAs have been identified from high-throughput RNA-seq datasets. However, functional annotation and prioritization of these circRNAs for further experimental validation and functional investigation is the bottleneck step for current circRNA studies.
Now, we have updated circAltas 2.0 to circAtlas 3.0 (current version) , which integrates more than over 3.1 million circRNAs across 10 species (human, macaque, mouse, rat, pig, chicken, dog, sheep, cat, rabbit) and a variety of tissues. The circAtlas 3.0 can fill this gap by integrating the most comprehensive circRNAs and their expression and functional profiles in vertebrates, providing a foundation for circRNA studies and serving as a powerful starting point for investigating their biological significance.