Dataset

Data release 1.0

Omics	Disease	Tissue/cell type	Method	Number of samples	CVD Atlas ID	GEO link
Transcriptomics	Intracranial aneurysm	Neutrophil	RNA-seq	32	CVDS000004	GSE106520

Search:

GEO accession	Run	BioSample	Experiment	Reported condition	Mapped Condition	Tissue
GSM2839721	SRR6255415	SAMN07977096	SRX3361930	Control	Control	neutrophils
GSM2839722	SRR6255416	SAMN07977097	SRX3361931	Control	Control	neutrophils
GSM2839723	SRR6255417	SAMN07977098	SRX3361932	Control	Control	neutrophils
GSM2839724	SRR6255418	SAMN07977099	SRX3361933	Control	Control	neutrophils
GSM2839725	SRR6255419	SAMN07977100	SRX3361934	Control	Control	neutrophils
GSM2839726	SRR6255420	SAMN07977087	SRX3361935	Control	Control	neutrophils
GSM2839727	SRR6255421	SAMN07977088	SRX3361936	Control	Control	neutrophils
GSM2839728	SRR6255422	SAMN07977089	SRX3361937	Control	Control	neutrophils
GSM2839729	SRR6255423	SAMN07977090	SRX3361938	Control	Control	neutrophils
GSM2839730	SRR6255424	SAMN07977091	SRX3361939	Control	Control	neutrophils

Showing 1 to 10 of 32 entries

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Up: log2FC > 1 and adjusted P value <0.05
Down: log2FC < -1 and adjusted P value <0.05
Non-significant: -1 < log2FC < 1 or adjusted P value >0.05

Only show significant DEGs

Search:

Symbol	log2FC	P value	Adjusted P value	Group1	Group2
ENSG00000289474	6.72	2.56e-14	5.57e-10	Intracranial aneurysm	Control
MTRNR2L1	6.19	4.13e-11	4.49e-7	Intracranial aneurysm	Control
TBC1D3C	2.77	0.0526	1.00	Intracranial aneurysm	Control
ENSG00000258465	2.22	0.0190	1.00	Intracranial aneurysm	Control
ENSG00000287856	1.99	0.350	1.00	Intracranial aneurysm	Control
PCDH8	1.92	0.0754	1.00	Intracranial aneurysm	Control
MKKS	1.92	0.292	1.00	Intracranial aneurysm	Control
ENSG00000273262	1.82	0.0610	1.00	Intracranial aneurysm	Control
ENSG00000274177	1.77	0.287	1.00	Intracranial aneurysm	Control
CYP1B1	1.76	0.000130	0.464	Intracranial aneurysm	Control

Showing 1 to 10 of 18,137 entries

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Up regulated

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Ontology	GO ID	GO term	GeneRatio	BgRatio	P value	Adjusted P value	Q value	Gene count	Regulatory trend
BP	GO:1900118	negative regulation of execution phase of apoptosis	1/1	24/18866	1.27e-3	5.12e-3	NaN	1	Up
BP	GO:1900117	regulation of execution phase of apoptosis	1/1	41/18866	2.17e-3	5.12e-3	NaN	1	Up
BP	GO:2000272	negative regulation of signaling receptor activity	1/1	58/18866	3.07e-3	5.12e-3	NaN	1	Up
BP	GO:0097194	execution phase of apoptosis	1/1	95/18866	5.04e-3	6.29e-3	NaN	1	Up
BP	GO:0010469	regulation of signaling receptor activity	1/1	174/18866	9.22e-3	9.22e-3	NaN	1	Up
MF	GO:0048019	receptor antagonist activity	1/1	32/18352	1.74e-3	2.23e-3	NaN	1	Up
MF	GO:0030547	receptor inhibitor activity	1/1	41/18352	2.23e-3	2.23e-3	NaN	1	Up

Showing 1 to 7 of 7 entries

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Search:

Gene	Condition	Min	Q1	Median	Q3	Max
ENSG00000276663	Control	0	0.16	0.3	0.48	0.57
ENSG00000276663	Intracranial aneurysm	0.07	0.14	0.31	0.45	0.77

Showing 1 to 2 of 2 entries

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Module	Trait	Correlation	P value
magenta	Control	0.25	1.63e-1
greenyellow	Control	0.24	1.84e-1
royalblue	Intracranial aneurysm	0.21	2.51e-1
yellow	Control	0.19	2.94e-1
darkred	Control	0.19	3.06e-1

Showing 1 to 5 of 10 entries

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Module

Only top 100 pairs are retained and displayed in network plot, ordered by 'Weight'.

Search:

Node 1	Node 2	Weight	Detail
ENSG00000269937	ENSG00000289091	0.143	Detail
ENSG00000250031	ENSG00000289091	0.136	Detail
RPL11P3	ENSG00000289091	0.132	Detail
ENSG00000251288	ENSG00000289091	0.131	Detail
ENSG00000289091	ENSG00000289504	0.130	Detail

Showing 1 to 5 of 100 entries

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