Cardiovascular Disease Atlas
Data release 1.0
| Symbol | CVD Atlas ID | Species | Gene ID | Biotype | Chr | Start | End |
|---|---|---|---|---|---|---|---|
| TBC1D3C | CVDG011270 | Homo sapiens | ENSG00000278299 | Protein coding | 17 | 38057693 | 38068634 |
| Disease or trait | Score |
|---|---|
| Atherosclerosis | 0.82618 |
| Ischemic stroke | 0.7525 |
| Cardiovascular disease | 0.66055 |
| Intracranial aneurysm | 0.66055 |
| Myocardial infarction | 0.66055 |
| GO ID | GO term | Category |
|---|
| Tissue/cell type | Disease | Condition 1 | Condition 2 | Alteration | log2FC | P value | Adjusted P value | Method | PMID |
|---|---|---|---|---|---|---|---|---|---|
| Plasma | Acute coronary syndrome | Acute coronary syndrome | Control | Down | -1.20 | - | - | RNA-seq | 31899480 |
| Dataset | Tissue/cell type | Reported disease | Mapped disease | log2FC | P value | Adjusted P value | Method | GEO accession |
|---|---|---|---|---|---|---|---|---|
| No data available in table | ||||||||
| Reported disease | Mapped disease | RNADisease score | PMID | Gene link |
|---|---|---|---|---|
| Cardiovascular Disease | Cardiovascular disease | 0.635617 | 33563011 | RNADisease |
| Reported disease/trait | Mapped trait | Tissue | Effect size | P value | Method | Publication | PMID | Gene link |
|---|---|---|---|---|---|---|---|---|
| No data available in table | ||||||||
| Reported disease | Mapped disease | Category | Description | Publication |
|---|---|---|---|---|
| Stroke | Stroke | circulation_biomarker_diagnosis_up | After adjusting for potential confounders, we found plasma levels of 3 miRNAs to be associated with incident stroke (false discovery rate-adjusted P<0.05). These include miR-6124 (hazard ratio, 1.66 [95% CI, 1.31-2.09]), miR-5196-5p (hazard ratio, 1.90 [95% CI, 1.39-2.61]), and miR-4292 (hazard ratio, 2.65 [95% CI, 1.62-4.34]). | 33563011 |
| Reported disease | Mapped disease | Species | Description | Publication |
|---|---|---|---|---|
| No data available in table | ||||
| Variant | Reported disease/trait | Mapped disease/trait | Beta | Standard error | P value | Odds ratio | Ancestry | Dataset | Link |
|---|
| Reported disease/trait | Mapped disease/trait | Tissue | Best coloc SNP | GWAS risk SNP | SNP.PP.H4 | PP.H4.abf | Ancestry | Dataset |
|---|
| Variant | Reported disease | Mapped disease | Description | PMID |
|---|---|---|---|---|
| No data available in table | ||||
| Variant | Disease | Pre miRNA | Region | Mature miRNA | △G | Exp | PMID |
|---|---|---|---|---|---|---|---|
| No data available in table | |||||||
| Reported disease | Gene | Category | Description | Publication |
|---|---|---|---|---|
| No data available in table | ||||
| SNP | Reported disease | Mapped disease | Description | PMID |
|---|---|---|---|---|
| No data available in table | ||||
| Name | Delta beta | P value | Adjusted P value | Reported disease | Mapped disease | Dataset |
|---|---|---|---|---|---|---|
| No data available in table | ||||||
| Name | Relation to gene | Delta beta | P value | Adjusted P value | Tissue | Reported disease | Mapped disease | Condition 1 | Condition 2 | PMID |
|---|---|---|---|---|---|---|---|---|---|---|
| No data available in table | ||||||||||
| Reported disease | Mapped disease | Category | Description | Publication |
|---|---|---|---|---|
| No data available in table | ||||
| Reported disease | Mapped disease | Species | Description | Publication |
|---|---|---|---|---|
| No data available in table | ||||
| UniProt ID | Reported disease | Mapped disease | Average log2FC | P value | Dataset |
|---|---|---|---|---|---|
| No data available in table | |||||
| Gene | PharmGKB gene ID | Chemical | PharmGKB chemical ID | Evidence | Association |
PK/PD
| PMID |
|---|---|---|---|---|---|---|---|
| No data available in table | |||||||
| Chemical name | Chemical ID | Reported disease | Mapped disease | Inference score | #PMIDs | Gene link |
|---|