Dataset

Data release 1.0

CVD Atlas ID	CVDS000349
Data type	GWAS summary statistics
Disease/trait	Intermediate density lipoprotein measurement
Title	Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation.
PubMed ID	35213538
GWAS Catalog link	GCST90092838

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Gene	Tissue	#SNPs	PP.H4.abf	PP4/PP3	Coloc SNP	GWAS risk SNP	PP.H0.abf	PP.H1.abf	PP.H2.abf	PP.H3.abf
ABCA10	Brain_Cerebellum	14	0.90	80.4	rs8070232	rs77542162	9.67e-5	8.91e-2	1.31e-5	1.12e-2
ABCA10	Brain_Cerebellar_Hemisphere	27	0.90	22.6	rs8070232	rs77542162	6.74e-5	6.22e-2	4.41e-5	3.97e-2
ABCA5	Heart_Atrial_Appendage	21	0.95	254	rs1468512	rs77542162	8.91e-4	1.00e-4	4.18e-2	3.75e-3
ABCA5	Brain_Nucleus_accumbens_basal_ganglia	9	0.92	92.0	rs62080889	rs77542162	4.64e-4	7.48e-2	6.74e-5	9.95e-3
ABCA6	Brain_Cortex	24	0.86	16.5	rs2886232	rs77542162	1.05e-5	9.21e-2	5.98e-6	5.18e-2
ABCG5	Spleen	67	0.80	3.90	rs115445558	rs4299376	8.47e-23	4.71e-4	3.69e-20	2.04e-1
ABCG5	Colon_Transverse	2	0.96	5.84e+4	rs4245791	rs4299376	4.24e-22	4.20e-2	9.83e-24	1.64e-5
ABCG8	Spleen	60	0.83	6.43	rs115445558	rs4299376	7.54e-21	4.19e-2	2.33e-20	1.29e-1
ABCG8	Colon_Transverse	14	0.99	144	rs4299376	rs4299376	4.06e-33	8.97e-12	3.57e-24	6.89e-3
ABCG8	Adipose_Visceral_Omentum	23	0.91	81.8	rs139029940	rs4299376	1.41e-2	2.65e-3	6.42e-2	1.11e-2

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