Cardiovascular Disease Atlas
Data release 1.0
| Symbol | CVD Atlas ID | Species | Gene ID | Biotype | Chr | Start | End |
|---|---|---|---|---|---|---|---|
| ABCG8 | CVDG019816 | Homo sapiens | ENSG00000143921 | Protein coding | 2 | 43831942 | 43882988 |
| Disease or trait | Score |
|---|---|
| Low density lipoprotein cholesterol measurement | 0.90733 |
| Coronary artery disease | 0.85382 |
| Total cholesterol measurement | 0.84072 |
| Hypercholesterolemia | 0.71857 |
| Triglyceride measurement | 0.71857 |
| GO ID | GO term | Category |
|---|
| Tissue/cell type | Disease | Condition 1 | Condition 2 | Alteration | log2FC | P value | Adjusted P value | Method | PMID |
|---|---|---|---|---|---|---|---|---|---|
| No data available in table | |||||||||
| Dataset | Tissue/cell type | Reported disease | Mapped disease | log2FC | P value | Adjusted P value | Method | GEO accession |
|---|---|---|---|---|---|---|---|---|
| CVDS000002 | Blood | Cerebral infarction | Cerebral infarction | 2.22 | 2.40e-7 | 1.19e-4 | Microarray | GSE102541 |
| CVDS000552 | Brain | Cerebral Cavernous Malformation | Cerebral cavernous malformation | -1.66 | 4.71e-6 | 2.32e-5 | RNA-seq | GSE137596 |
| Reported disease | Mapped disease | RNADisease score | PMID | Gene link |
|---|---|---|---|---|
| No data available in table | ||||
| Reported disease | Mapped disease | Category | Description | Publication |
|---|---|---|---|---|
| No data available in table | ||||
| Reported disease | Mapped disease | Species | Description | Publication |
|---|---|---|---|---|
| No data available in table | ||||
| Variant | Reported disease/trait | Mapped disease/trait | Beta | Standard error | P value | Odds ratio | Ancestry | Dataset | Link |
|---|
| Reported disease/trait | Mapped disease/trait | Tissue | Best coloc SNP | GWAS risk SNP | SNP.PP.H4 | PP.H4.abf | Ancestry | Dataset |
|---|
| Variant | Reported disease | Mapped disease | Description | PMID |
|---|---|---|---|---|
| rs11887534 | Coronary artery disease | Coronary artery disease | Effect of genetic variant (rs11887534) in ABCG8 gene in coronary artery disease and response to atorvastatin therapy. | 20592455 |
| Variant | Disease | Pre miRNA | Region | Mature miRNA | △G | Exp | PMID |
|---|---|---|---|---|---|---|---|
| No data available in table | |||||||
| Reported disease | Gene | Category | Description | Publication |
|---|---|---|---|---|
| No data available in table | ||||
| SNP | Reported disease | Mapped disease | Description | PMID |
|---|---|---|---|---|
| rs6756629 | LDL cholesterol | Low density lipoprotein cholesterol measurement | OR: 1.17; P value: 2.6e-10; Beta: 0.16; SE: 0.02; Ancestry: European | 19060911 |
| Name | Delta beta | P value | Adjusted P value | Reported disease | Mapped disease | Dataset |
|---|---|---|---|---|---|---|
| No data available in table | ||||||
| Name | Relation to gene | Delta beta | P value | Adjusted P value | Tissue | Reported disease | Mapped disease | Condition 1 | Condition 2 | PMID |
|---|---|---|---|---|---|---|---|---|---|---|
| No data available in table | ||||||||||
| Reported disease | Mapped disease | Category | Description | Publication |
|---|---|---|---|---|
| No data available in table | ||||
| Reported disease | Mapped disease | Species | Description | Publication |
|---|---|---|---|---|
| No data available in table | ||||
| UniProt ID | Reported disease | Mapped disease | Average log2FC | P value | Dataset |
|---|---|---|---|---|---|
| No data available in table | |||||
| Chemical name | Chemical ID | Reported disease | Mapped disease | Inference score | #PMIDs | Gene link |
|---|