Residual blood samples, originally collected for the routine assessment of Tac levels after LTx, were repurposed for genotype analysis. A detailed list of the SNPs examined in this study is provided in Supplementary Table S1. For genotyping, a 0.5 mL blood sample was collected and genomic DNA was extracted from EDTA-anticoagulated peripheral blood using a commercially available DNA purification kit (EasyPure Blood Genomic DNA Kit, Transgene Biotech, Beijing, China). Samples with a call rate > 95% were genotyped using an ASACHIA Bead chip (Infinium Asian Screening Array-China Health Industry Alliance) according to the Illumina Infinium HTS chip standard operating procedures.