Submission GVM000313
2022-03-16
Tianjin Medical University Cancer Hospital
OrganismHomo sapiens
Versionhg19
BioProjectPRJCA008659
Sample numbers11904
Abstract

Sequencing data of cell-free DNA from plasma and genomic DNA from matched peripheral blood lymphocyte in 11904 Chinese pan-cancer patients were analyzed for determining PIK3CA mutation status and compared with genomic data from the Catalogue of Somatic Mutations in Cancer (COSMIC) database. Meanwhile, concomitant genomic aberrations in PIK3CA-mutated samples were detected to investigate cancer driver genes and their enriched pathways. Besides, the tumor samples were screened for mutations in Alpelisib-targeted genes, and the potential actionable co-alterations were analyzed by using the OncoKB classification.

Data Accessibility:Controlled access   
Release date2024-03-17
Available data
data submitter: huangqingfeng@tjmuch.com
P1.somatic.txt
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P11518.somatic.txt
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P11520.somatic.txt
P11521.somatic.txt
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P11558.somatic.txt
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P11560.somatic.txt
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P11562.somatic.txt
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P11564.somatic.txt
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P11571.somatic.txt
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P11577.somatic.txt
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P11579.somatic.txt
P11580.somatic.txt
P11581.somatic.txt
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P11588.somatic.txt
P11589.somatic.txt
P11590.somatic.txt
P11591.somatic.txt
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P11599.somatic.txt
P11600.somatic.txt
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P11608.somatic.txt
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P11610.somatic.txt
P11611.somatic.txt
P11612.somatic.txt
P11613.somatic.txt
P11614.somatic.txt
P11615.somatic.txt
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P11650.somatic.txt
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P11660.somatic.txt
P11661.somatic.txt
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P11664.somatic.txt
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P11666.somatic.txt
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P11669.somatic.txt
P11670.somatic.txt
P11671.somatic.txt
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P11680.somatic.txt
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P11699.somatic.txt
P11700.somatic.txt
P11701.somatic.txt
P11702.somatic.txt
P11703.somatic.txt
P11704.somatic.txt
P11705.somatic.txt
P11706.somatic.txt
P11707.somatic.txt
P11708.somatic.txt
P11709.somatic.txt
P11710.somatic.txt
P11711.somatic.txt
P11712.somatic.txt
P11713.somatic.txt
P11714.somatic.txt
P11715.somatic.txt
P11716.somatic.txt
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P11720.somatic.txt
P11721.somatic.txt
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P11764.somatic.txt
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P11768.somatic.txt
P11769.somatic.txt
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P11810.somatic.txt
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P11812.somatic.txt
P11813.somatic.txt
P11814.somatic.txt
P11815.somatic.txt
P11816.somatic.txt
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P11875.somatic.txt
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