Submission GVM000313
2022-03-16
Tianjin Medical University Cancer Hospital
OrganismHomo sapiens
Versionhg19
BioProjectPRJCA008659
Sample numbers11904
Abstract

Sequencing data of cell-free DNA from plasma and genomic DNA from matched peripheral blood lymphocyte in 11904 Chinese pan-cancer patients were analyzed for determining PIK3CA mutation status and compared with genomic data from the Catalogue of Somatic Mutations in Cancer (COSMIC) database. Meanwhile, concomitant genomic aberrations in PIK3CA-mutated samples were detected to investigate cancer driver genes and their enriched pathways. Besides, the tumor samples were screened for mutations in Alpelisib-targeted genes, and the potential actionable co-alterations were analyzed by using the OncoKB classification.

Data Accessibility:Controlled access   
Release date2024-03-17
Available data
data submitter: huangqingfeng@tjmuch.com
P1.somatic.txt
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P10699.somatic.txt
P10700.somatic.txt
P10701.somatic.txt
P10702.somatic.txt
P10703.somatic.txt
P10704.somatic.txt
P10705.somatic.txt
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