LncRNA - LncRNAWiki

Basic Information

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Symbol	NEAT1
Synonyms	VINC,NA,LINC00084,MENepsilon/beta,NCRNA00084,TncRNA
Gene ID	HSALNG0084892
Gene Locus	11q13.1
Transcript ID	Show all transcript ID HSALNT0176751 HSALNT0176753 HSALNT0176757 HSALNT0176758 HSALNT0176759 HSALNT0176762 HSALNT0176765 HSALNT0289192 HSALNT0363258 HSALNT0363259 HSALNT0363260 HSALNT0363261 HSALNT0363262 HSALNT0363263 HSALNT0363264 HSALNT0363265 HSALNT0363266 HSALNT0363267 HSALNT0363268 HSALNT0363269 HSALNT0363270 HSALNT0363271 HSALNT0363272 HSALNT0363273 HSALNT0363274 HSALNT0363275 HSALNT0363276 HSALNT0363277 HSALNT0363278 HSALNT0363279 HSALNT0363280 HSALNT0363281 HSALNT0363282 HSALNT0363283 HSALNT0363284 HSALNT0363285 HSALNT0363286 HSALNT0363287 HSALNT0363289
Conservation	Y-NA-Placental mammal

Publication

240

Context

Sample

322

Disease

Signature

Interaction

Drug

sgRNA

Function

Conservation

Biological Context

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Table

Biological Context	Context Detail	Entry Count

Experimental Sample

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Table

Tissue/Cell Line	Entry Count

Drugs

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Table

Drug	Biological Context	Context Detail	PMID
Drug	Biological Context	Context Detail

Interacting Partner

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Target
Regulator

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Regulator Type	Regulator	Regulator Effect	Biological Context	Context Detail	PMID

PCG	PRAM1	Inhibit	Disease	acute promyelocytic leukemia	25245097
TF	CEBPB	Promote	Disease	acute promyelocytic leukemia	29111326
PCG	BRCA1	Inhibit	Disease	breast cancer	27556296
TF	POU5F1	Promote	Disease	lung cancer	28615056
TF	ESR1	Promote	Disease	prostate cancer	25415230
Protein	ELAVL1	NA			21572407
Protein	ELAVL1	NA			21723170
Protein	ELAVL1	NA			21723171
NA	Ezh2	NA			29138341
Protein	SMARCA4	NA			29520069

Showing 1 to 10 of 12 entries

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Target Type	Target	Target Effect	Biological Context	Context Detail	PMID

Protein	STAT3	Inhibit	Cell Differentiation	th17/cd4+ t	31119756
PCG	CDK5R1	Inhibit	Disease	alzheimer's disease	29997370
miRNA	miR-342-3p	Inhibit	Disease	atherosclerosis	30259979
miRNA	miR-181d-5p	NA	Disease	blood tumor	28185956
NA	FUS	NA	Disease	breast cancer	27147820
miRNA	miR-548	NA	Disease	breast cancer	27147820
miRNA	miR-129-5p	inhibit	Disease	breast cancer	27556296
PCG	WNT4	promote	Disease	breast cancer	27556296
miRNA	EZH2	NA	Disease	breast cancer	28034643
miRNA	miR-101-3p	NA	Disease	breast cancer	28034643

Showing 1 to 10 of 104 entries

Molecular Signature

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Genome Variation	Variation Detail	Biological Context	Context Detail	PMID

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Epigenetic Modification	Modification Detail	Biological Context	Context Detail	PMID

DNA methylation	cg14872693	Aging	aging	27029739
DNA methylation	cg12155547;cg15920975;cg23523668;cg20379593;cg02345399;cg09411730;cg20889322;cg07985890;cg22843803;cg24013589;cg24772412;cg11573318	Aging	aging	29064478
DNA methylation	cg09411730;cg15920975;cg23523668;cg20379593;cg12155547;cg03249011;cg09783493;cg07985890;cg22843803	Aging	aging	30626398
DNA methylation	cg02345399;cg12155547;cg15920975;cg23523668;cg22843803	Disease	b acute lymphoblastic leukemia with t(1;19)(q23;p13.3);e2a-pbx1(tcf3-pbx1)	26237075
DNA methylation	cg10416861	Disease	b acute lymphoblastic leukemia with t(12;21)(p13.2;q22.1);etv6-runx1	26237075
DNA methylation	cg24745327	Disease	behçet's disease	30863869
DNA methylation	demethylation	Disease	breast cancer	27556296
DNA methylation	cg00678239	Disease	breast cancer	29675884
DNA methylation	cg12637942	Disease	cerebral palsy	31035542
DNA methylation	cg26840755	Disease	chronic beryllium disease	30141971

Showing 1 to 10 of 34 entries

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Expression	Expression Detail	Biological Context	Context Detail	PMID
	Expression Detail
RNA	Differentially expressed	Disease	acquired immunodeficiency syndrome	23362321
RNA	Down-regulated	Disease	acute myeloid leukemia	30246348
RNA	Down-regulated	Disease	acute myeloid leukemia	32179410
RNA	Down-regulated	Disease	acute myeloid leukemia	32280304
RNA	Differentially expressed	Disease	acute promyelocytic leukemia	25245097
RNA	Differentially expressed	Disease	acute promyelocytic leukemia	29111326
RNA	Down-regulated	Disease	alzheimer's disease	29997370
RNA	Differentially expressed	Disease	amyotrophic lateral sclerosis	23835137
RNA	Up-regulated	Disease	anaplastic thyroid cancer	31485599
RNA	Up-regulated	Disease	anaplastic thyroid cancer	32336952

Showing 1 to 10 of 195 entries

Biological Function

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Biological Process	Molecular Function	Pathway	Functional Mechanism	Biological Context	Context Detail	PMID

NA	NA	Mapk signaling pathway	NA	Circadian		31173767
Apoptosis	NA	NA	NA	Disease	acute myeloid leukemia	30246348
Cell growth;Apoptosis	NA	NA	NA	Disease	acute myeloid leukemia	32179410
Cell growth;Apoptosis	NA	NA	NA	Disease	acute myeloid leukemia	32280304
Cell differentiation	NA	NA	NA	Disease	acute promyelocytic leukemia	25245097
Cell differentiation	NA	NA	Transcriptional regulation	Disease	acute promyelocytic leukemia	29111326
Autophagy;Apoptosis	NA	NA	NA	Disease	anaplastic thyroid cancer	31485599
Inflammatory response	NA	NA	Transcriptional regulation	Disease	atherosclerosis	30259979
Cell growth;Apoptosis	NA	NA	NA	Disease	bladder cancer	31933859
Tumorigenesis;Cell growth;Apoptosis	NA	NA	Epigenetic regulation	Disease	breast cancer	27556296

Showing 1 to 10 of 140 entries

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GO ID	Term	Gene Ratio	Adjust p-value	Count	Gene Symbol
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GO ID	Term	Gene Ratio	Adjust p-value	Count	Gene Symbol
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GO ID	Term	Gene Ratio	Adjust p-value	Count	Gene Symbol
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KEGG ID	Term	Gene Ratio	Adjust p-value	Count	Entrez ID
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GO ID	Term	Gene Ratio	Adjusted p-value	Count	Gene Symbol
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GO ID	Term	Gene Ratio	Adjusted p-value	Count	Gene Symbol
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GO ID	Term	Gene Ratio	Adjusted p-value	Count	Gene Symbol
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KEGG ID	Term	Gene Ratio	Adjusted p-value	Count	Entrez ID
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CRISPR Design

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sgRNA ID	sgRNA Sequence	sgRNA Position	sgRNA Pam	Length of sgRNA	sgRNA Type	sgRNA Validity	Cell Line	Note	PMID

Sequence

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search by accession id or nucleotide sequence

Transcript ID	Sequence

Curation History

Curated by:

Luo Sicheng(Fri Jul 29 13:40:50 CST 2022)

Luo Sicheng(Mon Aug 01 19:47:31 CST 2022)

Luo Sicheng(Tue Aug 02 16:08:13 CST 2022)

Luo Sicheng(Thu Mar 31 21:57:10 CST 2022)

Luo Sicheng(Tue Mar 29 16:22:25 CST 2022)

Luo Sicheng(Tue Mar 29 14:21:27 CST 2022)

Luo Sicheng(Wed Mar 23 10:10:32 CST 2022)

Wei Jing(Tue Jul 05 21:34:10 CST 2022)

Wei Jing(Sun Mar 20 16:24:57 CST 2022)

Wei Jing(Wed Jul 06 13:49:24 CST 2022)

Wei Jing(Wed Jul 06 10:54:51 CST 2022)

Wei Jing(Wed Jul 13 15:57:32 CST 2022)

Luo Sicheng(Wed Aug 03 18:12:24 CST 2022)

Reviewed by:

Luo Sicheng(Fri Jul 29 13:40:50 CST 2022)

Luo Sicheng(Mon Aug 01 19:47:31 CST 2022)

Luo Sicheng(Tue Aug 02 16:08:13 CST 2022)

Luo Sicheng(Thu Mar 31 21:57:10 CST 2022)

Luo Sicheng(Tue Mar 29 16:22:25 CST 2022)

Luo Sicheng(Tue Mar 29 14:21:27 CST 2022)

Luo Sicheng(Wed Mar 23 10:10:32 CST 2022)

Wei Jing(Tue Jul 05 21:34:10 CST 2022)

Wei Jing(Sun Mar 20 16:24:57 CST 2022)

Wei Jing(Wed Jul 06 13:49:24 CST 2022)

Wei Jing(Wed Jul 06 10:54:51 CST 2022)

Wei Jing(Wed Jul 13 15:57:32 CST 2022)

Luo Sicheng(Wed Aug 03 18:12:24 CST 2022)