OMIX002254

1Summary
Title Quartet RNAseq
Description As part of the Quartet Project for quality control and data integration of multiomics profiling, we established four RNA reference materials derived from immortalized B-lymphoblastoid cell lines from four members of a monozygotic twin family. Additionally, RNAseq datasets from the Quartet RNA reference materials were then collected, consisting of 252 RNAseq libraries from 21 batches generated in eight labs using two library construction protocols (poly(A) selection and RiboZero) and two sequencing platforms (Illumina NovaSeq and MGI DNBSEQ-T7).
Organism Homo sapiens
Data Type Expression Profiling by NGS
Data Accessibility Open-access
BioProject PRJCA012423
Release Date 2024-10-11
Submitter Yuanting Zheng (zhengyuanting@fudan.edu.cn)
Organization Fudan University
Submission Date 2022-11-01
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX002254-01 Count matrix of multi-batch RNAseq dataset 1 Expression Profiling by NGS 40.7 MB csv
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
Quartet RNA reference materials improve the quality of transcriptomic data through ratio-based profiling Nature Biotechnology 2023-07 OMIX002254 Deposit
Multi-omics data integration using ratio-based quantitative profiling with Quartet reference materials Nature Biotechnology 2023-09 OMIX002214 OMIX004562 OMIX002260 OMIX002254 OMIX002234 Deposit
Construction of RNA reference materials for improving the quantification of transcriptomic data Nature Protocols 2025-02 OMIX002254 Deposit
The Quartet Data Portal: integration of community-wide resources for multiomics quality control Genome Biology 2023-10 OMIX002214 OMIX004562 OMIX002260 OMIX002254 OMIX002234 Deposit
Haplotype-resolved assemblies and variant benchmark of a Chinese Quartet Genome Biology 2023-12 OMIX002260 OMIX002254 OMIX002234 OMIX002214 Deposit
Assessing and mitigating batch effects in large-scale omics studies Genome Biology 2024-10 OMIX002254 Deposit

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