OMIX003688

1Summary
Title Multi-omics profiling characterizes the distinct features of small extracellular vesicles derived from breast cancer tissues and 3D-culture models
Description Small extracellular vesicles (sEVs) are nanometric vesicles (less than 200 nm in diameter), enveloped by a lipid bi-layer and formed in vesicular bodies with the endosomal network. In this study, we isolated and characterized sEVs directly from fresh human breast cancer tissues (T-sEVs), paired normal tissues (N-sEVs) and corresponding plasma (B-sEVs), meanwhile we also collected sEVs from the paired tumor OTS (S-sEVs) and organoid (O-sEVs) models as well. By examining both transcriptomes and proteomes of sEVs from these various sources, we tried to identify the actual breast cancer-specific sEV signatures, and illuminate the key different features between sEVs derived from the fresh tissues and the commonly used in vitro models.
Organism Homo sapiens
Data Type Proteomic Data by Mass Spectrometry (MS)
Data Accessibility Controlled-access
BioProject PRJCA013091
Release Date 2024-05-06
Submitter Chao Ni (davenc@163.com)
Organization The Second Affiliated Hospital, Zhejiang University School of Medicine
Submission Date 2023-04-10
Request for this Data
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX003688-01 O7-1 1 Proteomic Data by Mass Spectrometry (MS) 1.34 GB zip Controlled
OMIX003688-02 B3-1 1 Proteomic Data by Mass Spectrometry (MS) 1.41 GB zip Controlled
OMIX003688-03 S9-1 1 Proteomic Data by Mass Spectrometry (MS) 5.11 GB zip Controlled
OMIX003688-04 O8-2 1 Proteomic Data by Mass Spectrometry (MS) 1.99 GB zip Controlled
OMIX003688-05 N1-2 1 Proteomic Data by Mass Spectrometry (MS) 5.68 GB zip Controlled
OMIX003688-06 B1-2 1 Proteomic Data by Mass Spectrometry (MS) 6.39 GB zip Controlled
OMIX003688-07 B5-1 1 Proteomic Data by Mass Spectrometry (MS) 5.57 GB zip Controlled
OMIX003688-08 T1-2 1 Proteomic Data by Mass Spectrometry (MS) 6.23 GB zip Controlled
OMIX003688-09 S10-2 1 Proteomic Data by Mass Spectrometry (MS) 501.86 MB zip Controlled
OMIX003688-10 T9-1 1 Proteomic Data by Mass Spectrometry (MS) 6.79 GB zip Controlled
OMIX003688-11 T9-2 1 Proteomic Data by Mass Spectrometry (MS) 6.96 GB zip Controlled
OMIX003688-12 O9-2 1 Proteomic Data by Mass Spectrometry (MS) 546.11 MB zip Controlled
OMIX003688-13 N9-1 1 Proteomic Data by Mass Spectrometry (MS) 3.55 GB zip Controlled
OMIX003688-14 O2-1 1 Proteomic Data by Mass Spectrometry (MS) 4.52 GB zip Controlled
OMIX003688-15 S7-1 1 Proteomic Data by Mass Spectrometry (MS) 814.15 MB zip Controlled
OMIX003688-16 T3-2 1 Proteomic Data by Mass Spectrometry (MS) 5.76 GB zip Controlled
OMIX003688-17 B4-1 1 Proteomic Data by Mass Spectrometry (MS) 2.63 GB zip Controlled
OMIX003688-18 B4-2 1 Proteomic Data by Mass Spectrometry (MS) 2.54 GB zip Controlled
OMIX003688-19 T3-1 1 Proteomic Data by Mass Spectrometry (MS) 5.71 GB zip Controlled
OMIX003688-20 T2-1 1 Proteomic Data by Mass Spectrometry (MS) 3.72 GB zip Controlled
OMIX003688-21 T4-2 1 Proteomic Data by Mass Spectrometry (MS) 4.13 GB zip Controlled
OMIX003688-22 S9-2 1 Proteomic Data by Mass Spectrometry (MS) 5.11 GB zip Controlled
OMIX003688-23 S4-1 1 Proteomic Data by Mass Spectrometry (MS) 2.93 GB zip Controlled
OMIX003688-24 N2-1 1 Proteomic Data by Mass Spectrometry (MS) 4.8 GB zip Controlled
OMIX003688-25 O9-1 1 Proteomic Data by Mass Spectrometry (MS) 567.11 MB zip Controlled
OMIX003688-26 B6-2 1 Proteomic Data by Mass Spectrometry (MS) 4.65 GB zip Controlled
OMIX003688-27 T2-2 1 Proteomic Data by Mass Spectrometry (MS) 3.87 GB zip Controlled
OMIX003688-28 O2-2 1 Proteomic Data by Mass Spectrometry (MS) 4.44 GB zip Controlled
OMIX003688-29 N3-2 1 Proteomic Data by Mass Spectrometry (MS) 5.21 GB zip Controlled
OMIX003688-30 N3-1 1 Proteomic Data by Mass Spectrometry (MS) 5.15 GB zip Controlled
OMIX003688-31 O1-1 1 Proteomic Data by Mass Spectrometry (MS) 2.57 GB zip Controlled
OMIX003688-32 O1-2 1 Proteomic Data by Mass Spectrometry (MS) 2.51 GB zip Controlled
OMIX003688-33 T1-1 1 Proteomic Data by Mass Spectrometry (MS) 6.25 GB zip Controlled
OMIX003688-34 S2-1 1 Proteomic Data by Mass Spectrometry (MS) 1.37 GB zip Controlled
OMIX003688-35 O3-2 1 Proteomic Data by Mass Spectrometry (MS) 4.32 GB zip Controlled
OMIX003688-36 O7-2 1 Proteomic Data by Mass Spectrometry (MS) 1.37 GB zip Controlled
OMIX003688-37 T7-2 1 Proteomic Data by Mass Spectrometry (MS) 5.61 GB zip Controlled
OMIX003688-38 N1-1 1 Proteomic Data by Mass Spectrometry (MS) 5.63 GB zip Controlled
OMIX003688-39 T7-1 1 Proteomic Data by Mass Spectrometry (MS) 5.62 GB zip Controlled
OMIX003688-40 N8-1 1 Proteomic Data by Mass Spectrometry (MS) 5.77 GB zip Controlled
OMIX003688-41 N2-2 1 Proteomic Data by Mass Spectrometry (MS) 5 GB zip Controlled
OMIX003688-42 N5-1 1 Proteomic Data by Mass Spectrometry (MS) 4.61 GB zip Controlled
OMIX003688-43 S5-1 1 Proteomic Data by Mass Spectrometry (MS) 3.58 GB zip Controlled
OMIX003688-44 S5-2 1 Proteomic Data by Mass Spectrometry (MS) 3.98 GB zip Controlled
OMIX003688-45 S7-2 1 Proteomic Data by Mass Spectrometry (MS) 665.15 MB zip Controlled
OMIX003688-46 T5-2 1 Proteomic Data by Mass Spectrometry (MS) 7.39 GB zip Controlled
OMIX003688-47 S6-2 1 Proteomic Data by Mass Spectrometry (MS) 5.16 GB zip Controlled
OMIX003688-48 B5-2 1 Proteomic Data by Mass Spectrometry (MS) 5.45 GB zip Controlled
OMIX003688-49 N4-2 1 Proteomic Data by Mass Spectrometry (MS) 729.94 MB zip Controlled
OMIX003688-50 B2-1 1 Proteomic Data by Mass Spectrometry (MS) 2.73 GB zip Controlled
OMIX003688-51 B7-1 1 Proteomic Data by Mass Spectrometry (MS) 4.68 GB zip Controlled
OMIX003688-52 S6-1 1 Proteomic Data by Mass Spectrometry (MS) 5.06 GB zip Controlled
OMIX003688-53 S10-1 1 Proteomic Data by Mass Spectrometry (MS) 504.39 MB zip Controlled
OMIX003688-54 S8-2 1 Proteomic Data by Mass Spectrometry (MS) 4.89 GB zip Controlled
OMIX003688-55 N7-2 1 Proteomic Data by Mass Spectrometry (MS) 5.04 GB zip Controlled
OMIX003688-56 N3-3 1 Proteomic Data by Mass Spectrometry (MS) 4.96 GB zip Controlled
OMIX003688-57 N5-2 1 Proteomic Data by Mass Spectrometry (MS) 4.73 GB zip Controlled
OMIX003688-58 B3-2 1 Proteomic Data by Mass Spectrometry (MS) 1.29 GB zip Controlled
OMIX003688-59 S3-2 1 Proteomic Data by Mass Spectrometry (MS) 3.3 GB zip Controlled
OMIX003688-60 N8-2 1 Proteomic Data by Mass Spectrometry (MS) 5.99 GB zip Controlled
OMIX003688-61 S2-2 1 Proteomic Data by Mass Spectrometry (MS) 1.41 GB zip Controlled
OMIX003688-62 O4-1 1 Proteomic Data by Mass Spectrometry (MS) 4.57 GB zip Controlled
OMIX003688-63 O5-1 1 Proteomic Data by Mass Spectrometry (MS) 4.79 GB zip Controlled
OMIX003688-64 B7-2 1 Proteomic Data by Mass Spectrometry (MS) 4.51 GB zip Controlled
OMIX003688-65 B6-1 1 Proteomic Data by Mass Spectrometry (MS) 4.63 GB zip Controlled
OMIX003688-66 B1-1 1 Proteomic Data by Mass Spectrometry (MS) 6.48 GB zip Controlled
OMIX003688-67 O4-2 1 Proteomic Data by Mass Spectrometry (MS) 4.36 GB zip Controlled
OMIX003688-68 S3-1 1 Proteomic Data by Mass Spectrometry (MS) 3.17 GB zip Controlled
OMIX003688-69 T6-2 1 Proteomic Data by Mass Spectrometry (MS) 5.9 GB zip Controlled
OMIX003688-70 N4-1 1 Proteomic Data by Mass Spectrometry (MS) 764.47 MB zip Controlled
OMIX003688-71 B2-2 1 Proteomic Data by Mass Spectrometry (MS) 2.69 GB zip Controlled
OMIX003688-72 T6-1 1 Proteomic Data by Mass Spectrometry (MS) 5.8 GB zip Controlled
OMIX003688-73 06-2 1 Proteomic Data by Mass Spectrometry (MS) 1.34 GB zip Controlled
OMIX003688-74 T4-1 1 Proteomic Data by Mass Spectrometry (MS) 4.21 GB zip Controlled
OMIX003688-75 O5-2 1 Proteomic Data by Mass Spectrometry (MS) 4.8 GB zip Controlled
OMIX003688-76 T8-1 1 Proteomic Data by Mass Spectrometry (MS) 1.49 GB zip Controlled
OMIX003688-77 T8-2 1 Proteomic Data by Mass Spectrometry (MS) 1.5 GB zip Controlled
OMIX003688-78 S4-2 1 Proteomic Data by Mass Spectrometry (MS) 2.88 GB zip Controlled
OMIX003688-79 O3-1 1 Proteomic Data by Mass Spectrometry (MS) 4.34 GB zip Controlled
OMIX003688-80 S1-1 1 Proteomic Data by Mass Spectrometry (MS) 660.24 MB zip Controlled
OMIX003688-81 N9-2 1 Proteomic Data by Mass Spectrometry (MS) 3.79 GB zip Controlled
OMIX003688-82 S8-1 1 Proteomic Data by Mass Spectrometry (MS) 4.8 GB zip Controlled
OMIX003688-83 O8-1 1 Proteomic Data by Mass Spectrometry (MS) 2.05 GB zip Controlled
OMIX003688-84 N7-1 1 Proteomic Data by Mass Spectrometry (MS) 4.9 GB zip Controlled
OMIX003688-85 S1-2 1 Proteomic Data by Mass Spectrometry (MS) 573.06 MB zip Controlled
OMIX003688-86 N6-1 1 Proteomic Data by Mass Spectrometry (MS) 11.87 GB zip Controlled
OMIX003688-87 O6-1 1 Proteomic Data by Mass Spectrometry (MS) 1.35 GB zip Controlled
OMIX003688-88 T5-1 1 Proteomic Data by Mass Spectrometry (MS) 7.25 GB zip Controlled
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
Integrated transcriptomics, proteomics, and functional analysis to characterize the tissue‐specific small extracellular vesicle network of breast cancer MedComm 2023-12 OMIX003688 Deposit

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