Full-length Immune Repertoire Reconstruction and Profiling at the Transcriptome Level Using Long Read Sequencing
| Title | Full-length Immune Repertoire Reconstruction and Profiling at the Transcriptome Level Using Long Read Sequencing |
|---|---|
| Description | Here, we have developed a targeted full-length BCR/TCR transcript sequencing workflow (FLIRseq) with high accuracy and quantitative ability based on nanopore sequencing platforms. Then, FLIRseq was applied to characterize BCR/TCR repertoires of peripheral blood from healthy controls (HC), patients with acute lymphocytic leukemia (ALL), and patients with allergic diseases (AD), tumor-infiltrating lymphocytes (TILs) in prostate cancer tissues, and lymphocytes in psoriasis tissues. |
| Organism | Homo sapiens |
| Data Type | Expression Profiling by NGS |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA017924 |
| Release Date | 2024-08-23 |
| Submitter | Fei Xiao (xiaofei3965@bjhmoh.cn) |
| Organization | Beijing Hospital |
| Submission Date | 2023-06-27 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX004430-01 | reoriented consensus reads (tandem repeat more than 1) from AD1 | 1 | Expression Profiling by NGS | 5.62 MB | fasta | 0 | Unavailable |
| OMIX004430-02 | reoriented consensus reads (tandem repeat more than 1) from AD2 | 1 | Expression Profiling by NGS | 7.08 MB | fasta | 0 | Unavailable |
| OMIX004430-03 | reoriented consensus reads (tandem repeat more than 1) from AD3 | 1 | Expression Profiling by NGS | 10.35 MB | fasta | 0 | Unavailable |
| OMIX004430-04 | reoriented consensus reads (tandem repeat more than 1) from B-ALL1-BBT | 1 | Expression Profiling by NGS | 1.77 MB | fasta | 0 | Unavailable |
| OMIX004430-05 | reoriented consensus reads (tandem repeat more than 1) from B-ALL1-BIT1 | 1 | Expression Profiling by NGS | 5.74 MB | fasta | 0 | Unavailable |
| OMIX004430-06 | reoriented consensus reads (tandem repeat more than 1) from B-ALL1-BIT2 | 1 | Expression Profiling by NGS | 6.7 MB | fasta | 0 | Unavailable |
| OMIX004430-07 | reoriented consensus reads (tandem repeat more than 1) from B-ALL1-BIT3 | 1 | Expression Profiling by NGS | 2.53 MB | fasta | 0 | Unavailable |
| OMIX004430-08 | reoriented consensus reads (tandem repeat more than 1) from B-ALL2-Alle1 | 1 | Expression Profiling by NGS | 7.57 MB | fasta | 0 | Unavailable |
| OMIX004430-09 | reoriented consensus reads (tandem repeat more than 1) from B-ALL2-Alle2 | 1 | Expression Profiling by NGS | 4 MB | fasta | 0 | Unavailable |
| OMIX004430-10 | reoriented consensus reads (tandem repeat more than 1) from B-ALL2-Alle3 | 1 | Expression Profiling by NGS | 2.05 MB | fasta | 0 | Unavailable |
| OMIX004430-11 | reoriented consensus reads (tandem repeat more than 1) from B-ALL2-BBT | 1 | Expression Profiling by NGS | 20.31 MB | fasta | 0 | Unavailable |
| OMIX004430-12 | reoriented consensus reads (tandem repeat more than 1) from B-ALL3-Alle1 | 1 | Expression Profiling by NGS | 6.53 MB | fasta | 0 | Unavailable |
| OMIX004430-13 | reoriented consensus reads (tandem repeat more than 1) from B-ALL3-Alle2 | 1 | Expression Profiling by NGS | 4.93 MB | fasta | 0 | Unavailable |
| OMIX004430-14 | reoriented consensus reads (tandem repeat more than 1) from B-ALL3-BBT1 | 1 | Expression Profiling by NGS | 6.74 MB | fasta | 0 | Unavailable |
| OMIX004430-15 | reoriented consensus reads (tandem repeat more than 1) from B-ALL3-BBT2 | 1 | Expression Profiling by NGS | 2.15 MB | fasta | 0 | Unavailable |
| OMIX004430-16 | reoriented consensus reads (tandem repeat more than 1) from B-ALL3-BIT1 | 1 | Expression Profiling by NGS | 3.9 MB | fasta | 0 | Unavailable |
| OMIX004430-17 | reoriented consensus reads (tandem repeat more than 1) from B-ALL3-BIT2 | 1 | Expression Profiling by NGS | 2.7 MB | fasta | 0 | Unavailable |
| OMIX004430-18 | reoriented consensus reads (tandem repeat more than 1) from B-ALL4-Alle | 1 | Expression Profiling by NGS | 3 MB | fasta | 0 | Unavailable |
| OMIX004430-19 | reoriented consensus reads (tandem repeat more than 1) from B-ALL4-BBT | 1 | Expression Profiling by NGS | 1.65 MB | fasta | 0 | Unavailable |
| OMIX004430-20 | reoriented consensus reads (tandem repeat more than 1) from B-ALL4-BIT1 | 1 | Expression Profiling by NGS | 9.27 MB | fasta | 0 | Unavailable |
| OMIX004430-21 | reoriented consensus reads (tandem repeat more than 1) from B-ALL4-BIT2 | 1 | Expression Profiling by NGS | 3.23 MB | fasta | 0 | Unavailable |
| OMIX004430-22 | reoriented consensus reads (tandem repeat more than 1) from B-ALL5-Alle1 | 1 | Expression Profiling by NGS | 2.25 MB | fasta | 0 | Unavailable |
| OMIX004430-23 | reoriented consensus reads (tandem repeat more than 1) from B-ALL5-Alle2 | 1 | Expression Profiling by NGS | 2.95 MB | fasta | 0 | Unavailable |
| OMIX004430-24 | reoriented consensus reads (tandem repeat more than 1) from B-ALL5-BBT1 | 1 | Expression Profiling by NGS | 5.32 MB | fasta | 0 | Unavailable |
| OMIX004430-25 | reoriented consensus reads (tandem repeat more than 1) from B-ALL5-BBT2 | 1 | Expression Profiling by NGS | 4.44 MB | fasta | 0 | Unavailable |
| OMIX004430-26 | reoriented consensus reads (tandem repeat more than 1) from B-ALL5-BIT1 | 1 | Expression Profiling by NGS | 5.65 MB | fasta | 0 | Unavailable |
| OMIX004430-27 | reoriented consensus reads (tandem repeat more than 1) from B-ALL5-BIT2 | 1 | Expression Profiling by NGS | 8.91 MB | fasta | 0 | Unavailable |
| OMIX004430-28 | reoriented consensus reads (tandem repeat more than 1) from B-ALL6 | 1 | Expression Profiling by NGS | 10.18 MB | fasta | 0 | Unavailable |
| OMIX004430-29 | reoriented consensus reads (tandem repeat more than 1) from HC1 | 1 | Expression Profiling by NGS | 5.43 MB | fasta | 0 | Unavailable |
| OMIX004430-30 | reoriented consensus reads (tandem repeat more than 1) from HC10 | 1 | Expression Profiling by NGS | 5.26 MB | fasta | 0 | Unavailable |
| OMIX004430-31 | reoriented consensus reads (tandem repeat more than 1) from HC2 | 1 | Expression Profiling by NGS | 10.19 MB | fasta | 0 | Unavailable |
| OMIX004430-32 | reoriented consensus reads (tandem repeat more than 1) from HC3 | 1 | Expression Profiling by NGS | 10.02 MB | fasta | 0 | Unavailable |
| OMIX004430-33 | reoriented consensus reads (tandem repeat more than 1) from HC4 | 1 | Expression Profiling by NGS | 2.82 MB | fasta | 0 | Unavailable |
| OMIX004430-34 | reoriented consensus reads (tandem repeat more than 1) from HC5 | 1 | Expression Profiling by NGS | 5.39 MB | fasta | 0 | Unavailable |
| OMIX004430-35 | reoriented consensus reads (tandem repeat more than 1) from HC6 | 1 | Expression Profiling by NGS | 3.47 MB | fasta | 0 | Unavailable |
| OMIX004430-36 | reoriented consensus reads (tandem repeat more than 1) from HC7 | 1 | Expression Profiling by NGS | 3.71 MB | fasta | 0 | Unavailable |
| OMIX004430-37 | reoriented consensus reads (tandem repeat more than 1) from HC8 | 1 | Expression Profiling by NGS | 3.63 MB | fasta | 0 | Unavailable |
| OMIX004430-38 | reoriented consensus reads (tandem repeat more than 1) from HC9 | 1 | Expression Profiling by NGS | 1.44 MB | fasta | 0 | Unavailable |
| OMIX004430-39 | reoriented consensus reads (tandem repeat more than 1) from P1 | 1 | Expression Profiling by NGS | 2.08 MB | fasta | 0 | Unavailable |
| OMIX004430-40 | reoriented consensus reads (tandem repeat more than 1) from P2 | 1 | Expression Profiling by NGS | 1.29 MB | fasta | 0 | Unavailable |
| OMIX004430-41 | reoriented consensus reads (tandem repeat more than 1) from P3 | 1 | Expression Profiling by NGS | 1.25 MB | fasta | 0 | Unavailable |
| OMIX004430-42 | reoriented consensus reads (tandem repeat more than 1) from P4 | 1 | Expression Profiling by NGS | 935.68 KB | fasta | 0 | Unavailable |
| OMIX004430-43 | reoriented consensus reads (tandem repeat more than 1) from T-ALL1 | 1 | Expression Profiling by NGS | 21.03 MB | fasta | 0 | Unavailable |
| OMIX004430-44 | reoriented consensus reads (tandem repeat more than 1) from T-ALL2 | 1 | Expression Profiling by NGS | 35.63 MB | fasta | 0 | Unavailable |
| OMIX004430-45 | reoriented consensus reads (tandem repeat more than 1) from T1 | 1 | Expression Profiling by NGS | 19.29 MB | fasta | 0 | Unavailable |
| OMIX004430-46 | reoriented consensus reads (tandem repeat more than 1) from T2 | 1 | Expression Profiling by NGS | 13.12 MB | fasta | 0 | Unavailable |
| OMIX004430-47 | reoriented consensus reads (tandem repeat more than 1) from T3 | 1 | Expression Profiling by NGS | 12.01 MB | fasta | 0 | Unavailable |
| OMIX004430-48 | reoriented consensus reads (tandem repeat more than 1) from T4 | 1 | Expression Profiling by NGS | 7.17 MB | fasta | 0 | Unavailable |
| OMIX004430-49 | reoriented consensus reads (tandem repeat more than 1) from T5 | 1 | Expression Profiling by NGS | 4.69 MB | fasta | 0 | Unavailable |