OMIX004754

1Summary
Title GSTM2 alleviates heart failure via inhibiting DNA damage in cardiomyocytes
Description Heart failure (HF) seriously threatens human's health world widely. However, the pathological mechanisms of HF are still not fully clear. In this study, we performed proteomics and transcriptomics analysis to overview the detailed changes of proteins and mRNAs in HF with human heart failure samples and healthy donors, and found there was a great difference in the protein change pattern between the atrium and ventricle of HF myocardium. It is interested that metabolism model changed in ventricular tissue of HF samples, and inflammation pathways were activated in atrial tissues. Through analysis of the differentially expressed genes in the heart failure samples.
Organism Homo sapiens
Data Type Proteomic Data by Mass Spectrometry (MS)
Data Accessibility Controlled-access
BioProject PRJCA018941
Release Date 2024-02-02
Submitter Hongfei Xu (xuhongfei@zju.edu.cn)
Organization The First Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China
Submission Date 2023-08-16
Request for this Data
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX004754-01 C1LA 1 Proteomic Data by Mass Spectrometry (MS) 723.28 MB raw Controlled
OMIX004754-02 C2LA 2 Proteomic Data by Mass Spectrometry (MS) 732.54 MB raw Controlled
OMIX004754-03 C3LA 3 Proteomic Data by Mass Spectrometry (MS) 693.62 MB raw Controlled
OMIX004754-04 T1IVS 1 Proteomic Data by Mass Spectrometry (MS) 632.44 MB raw Controlled
OMIX004754-05 T1LA 1 Proteomic Data by Mass Spectrometry (MS) 669.6 MB raw Controlled
OMIX004754-06 T1LV 1 Proteomic Data by Mass Spectrometry (MS) 680.19 MB raw Controlled
OMIX004754-07 T1RA 1 Proteomic Data by Mass Spectrometry (MS) 722 MB raw Controlled
OMIX004754-08 T1RV 1 Proteomic Data by Mass Spectrometry (MS) 662.32 MB raw Controlled
OMIX004754-09 T2IVS 2 Proteomic Data by Mass Spectrometry (MS) 728.58 MB raw Controlled
OMIX004754-10 T2LA 2 Proteomic Data by Mass Spectrometry (MS) 679.17 MB raw Controlled
OMIX004754-11 T2LV 2 Proteomic Data by Mass Spectrometry (MS) 661.46 MB raw Controlled
OMIX004754-12 T2RA 2 Proteomic Data by Mass Spectrometry (MS) 729.03 MB raw Controlled
OMIX004754-13 T2RV 2 Proteomic Data by Mass Spectrometry (MS) 687.75 MB raw Controlled
OMIX004754-14 T3IVS 3 Proteomic Data by Mass Spectrometry (MS) 672.02 MB raw Controlled
OMIX004754-15 T3LA 3 Proteomic Data by Mass Spectrometry (MS) 705.5 MB raw Controlled
OMIX004754-16 T3LV 3 Proteomic Data by Mass Spectrometry (MS) 663.41 MB raw Controlled
OMIX004754-17 T3RA 3 Proteomic Data by Mass Spectrometry (MS) 678.02 MB raw Controlled
OMIX004754-18 T3RV 3 Proteomic Data by Mass Spectrometry (MS) 629.29 MB raw Controlled
OMIX004754-19 T4IVS 4 Proteomic Data by Mass Spectrometry (MS) 647.89 MB raw Controlled
OMIX004754-20 T4LA 4 Proteomic Data by Mass Spectrometry (MS) 733.04 MB raw Controlled
OMIX004754-21 T4LV 4 Proteomic Data by Mass Spectrometry (MS) 720.29 MB raw Controlled
OMIX004754-22 T4RA 4 Proteomic Data by Mass Spectrometry (MS) 747.9 MB raw Controlled
OMIX004754-23 T4RV 4 Proteomic Data by Mass Spectrometry (MS) 681.57 MB raw Controlled
OMIX004754-24 T5IVS 5 Proteomic Data by Mass Spectrometry (MS) 731.89 MB raw Controlled
OMIX004754-25 T5LA 5 Proteomic Data by Mass Spectrometry (MS) 743.87 MB raw Controlled
OMIX004754-26 T5LV 5 Proteomic Data by Mass Spectrometry (MS) 733.85 MB raw Controlled
OMIX004754-27 T5RA 5 Proteomic Data by Mass Spectrometry (MS) 750.06 MB raw Controlled
OMIX004754-28 T5RV 5 Proteomic Data by Mass Spectrometry (MS) 717.82 MB raw Controlled
OMIX004754-29 T6IVS 6 Proteomic Data by Mass Spectrometry (MS) 698.76 MB raw Controlled
OMIX004754-30 T6LA 6 Proteomic Data by Mass Spectrometry (MS) 743.07 MB raw Controlled
OMIX004754-31 T6LV 6 Proteomic Data by Mass Spectrometry (MS) 699.26 MB raw Controlled
OMIX004754-32 T6RA 6 Proteomic Data by Mass Spectrometry (MS) 741.76 MB raw Controlled
OMIX004754-33 T6RV 6 Proteomic Data by Mass Spectrometry (MS) 710.81 MB raw Controlled
OMIX004754-34 T7IVS 7 Proteomic Data by Mass Spectrometry (MS) 699.1 MB raw Controlled
OMIX004754-35 T7LA 7 Proteomic Data by Mass Spectrometry (MS) 763.01 MB raw Controlled
OMIX004754-36 T7LV 7 Proteomic Data by Mass Spectrometry (MS) 721.57 MB raw Controlled
OMIX004754-37 T7RA 7 Proteomic Data by Mass Spectrometry (MS) 734.43 MB raw Controlled
OMIX004754-38 T7RV 7 Proteomic Data by Mass Spectrometry (MS) 693.33 MB raw Controlled
OMIX004754-39 T8IVS 8 Proteomic Data by Mass Spectrometry (MS) 707.16 MB raw Controlled
OMIX004754-40 T8LA 8 Proteomic Data by Mass Spectrometry (MS) 760.56 MB raw Controlled
OMIX004754-41 T8LV 8 Proteomic Data by Mass Spectrometry (MS) 723.32 MB raw Controlled
OMIX004754-42 T8RA 8 Proteomic Data by Mass Spectrometry (MS) 738.51 MB raw Controlled
OMIX004754-43 T8RV 8 Proteomic Data by Mass Spectrometry (MS) 707.33 MB raw Controlled
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytes Cell & Bioscience 2023-11 OMIX004754 Deposit

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