Functional metagenomic and metabolomics analysis of gut dysbiosis induced by hyperoxia
| Title | Functional metagenomic and metabolomics analysis of gut dysbiosis induced by hyperoxia |
|---|---|
| Description | Inhaled oxygen is the first-line therapeutic approach for maintaining tissue oxygenation in critically ill patients, but usually exposes patients to damaging hyperoxia. Hyperoxia adversely increases the oxygen tension in the gut lumen which harbors the trillions of microorganisms playing an important role in host metabolism and immunity. Nevertheless, the effects of hyperoxia on gut microbiome and metabolome remain unclear, and metagenomic and metabolomics analysis were performed in this mouse study. |
| Organism | Mus musculus |
| Data Type | Metabolome Data by Mass Spectrometry (MS) |
| Data Accessibility | Open-access |
| BioProject | PRJCA022612 |
| Release Date | 2024-01-05 |
| Submitter | Zhouxiong Xing (xingzhouxiong111@126.com) |
| Organization | Affiliated Hospitaol of Zunyi Medical Universtiy |
| Submission Date | 2024-01-04 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX005581-01 | blood-negative ion mode-control1 | 16 | Metabolome Data by Mass Spectrometry (MS) | 307.21 MB | raw | 0 | |
| OMIX005581-02 | blood-negative ion mode-control2 | 16 | Metabolome Data by Mass Spectrometry (MS) | 355.66 MB | raw | 0 | |
| OMIX005581-03 | blood-negative ion mode-control3 | 16 | Metabolome Data by Mass Spectrometry (MS) | 298.23 MB | raw | 0 | |
| OMIX005581-04 | blood-negative ion mode-control4 | 16 | Metabolome Data by Mass Spectrometry (MS) | 301.08 MB | raw | 0 | |
| OMIX005581-05 | blood-negative ion mode-control5 | 16 | Metabolome Data by Mass Spectrometry (MS) | 305.65 MB | raw | 0 | |
| OMIX005581-06 | blood-negative ion mode-control6 | 16 | Metabolome Data by Mass Spectrometry (MS) | 297.57 MB | raw | 0 | |
| OMIX005581-07 | blood-negative ion mode-control7 | 16 | Metabolome Data by Mass Spectrometry (MS) | 290.04 MB | raw | 0 | |
| OMIX005581-08 | blood-negative ion mode-control8 | 16 | Metabolome Data by Mass Spectrometry (MS) | 306.01 MB | raw | 0 | |
| OMIX005581-09 | blood-negative ion mode-oxygen10 | 16 | Metabolome Data by Mass Spectrometry (MS) | 287.92 MB | raw | 0 | |
| OMIX005581-10 | blood-negative ion mode-oxygen11 | 16 | Metabolome Data by Mass Spectrometry (MS) | 284.57 MB | raw | 0 | |
| OMIX005581-11 | blood-negative ion mode-oxygen12 | 16 | Metabolome Data by Mass Spectrometry (MS) | 280.46 MB | raw | 0 | |
| OMIX005581-12 | blood-negative ion mode-oxygen13 | 16 | Metabolome Data by Mass Spectrometry (MS) | 290.26 MB | raw | 0 | |
| OMIX005581-13 | blood-negative ion mode-oxygen14 | 16 | Metabolome Data by Mass Spectrometry (MS) | 286.22 MB | raw | 0 | |
| OMIX005581-14 | blood-negative ion mode-oxygen15 | 16 | Metabolome Data by Mass Spectrometry (MS) | 287.31 MB | raw | 0 | |
| OMIX005581-15 | blood-negative ion mode-oxygen9 | 16 | Metabolome Data by Mass Spectrometry (MS) | 286.99 MB | raw | 0 | |
| OMIX005581-16 | blood-positive ion mode-control1 | 16 | Metabolome Data by Mass Spectrometry (MS) | 170.83 MB | raw | 0 | |
| OMIX005581-17 | blood-positive ion mode-control2 | 16 | Metabolome Data by Mass Spectrometry (MS) | 178.28 MB | raw | 0 | |
| OMIX005581-18 | blood-positive ion mode-control3 | 16 | Metabolome Data by Mass Spectrometry (MS) | 158.32 MB | raw | 0 | |
| OMIX005581-19 | blood-positive ion mode-control4 | 16 | Metabolome Data by Mass Spectrometry (MS) | 161.23 MB | raw | 0 | |
| OMIX005581-20 | blood-positive ion mode-control5 | 16 | Metabolome Data by Mass Spectrometry (MS) | 154.84 MB | raw | 0 | |
| OMIX005581-21 | blood-positive ion mode-control6 | 16 | Metabolome Data by Mass Spectrometry (MS) | 153.94 MB | raw | 0 | |
| OMIX005581-22 | blood-positive ion mode-control7 | 16 | Metabolome Data by Mass Spectrometry (MS) | 146.43 MB | raw | 0 | |
| OMIX005581-23 | blood-positive ion mode-control8 | 16 | Metabolome Data by Mass Spectrometry (MS) | 159.34 MB | raw | 0 | |
| OMIX005581-24 | blood-positive ion mode-oxygen10 | 16 | Metabolome Data by Mass Spectrometry (MS) | 155.32 MB | raw | 0 | |
| OMIX005581-25 | blood-positive ion mode-oxygen11 | 16 | Metabolome Data by Mass Spectrometry (MS) | 153.56 MB | raw | 0 | |
| OMIX005581-26 | blood-positive ion mode-oxygen12 | 16 | Metabolome Data by Mass Spectrometry (MS) | 148.89 MB | raw | 0 | |
| OMIX005581-27 | blood-positive ion mode-oxygen13 | 16 | Metabolome Data by Mass Spectrometry (MS) | 152.48 MB | raw | 0 | |
| OMIX005581-28 | blood-positive ion mode-oxygen14 | 16 | Metabolome Data by Mass Spectrometry (MS) | 145.38 MB | raw | 0 | |
| OMIX005581-29 | blood-positive ion mode-oxygen15 | 16 | Metabolome Data by Mass Spectrometry (MS) | 148.81 MB | raw | 0 | |
| OMIX005581-30 | blood-positive ion mode-oxygen9 | 16 | Metabolome Data by Mass Spectrometry (MS) | 154.85 MB | raw | 0 | |
| OMIX005581-31 | fecal pellet-negative ion mode-control1 | 16 | Metabolome Data by Mass Spectrometry (MS) | 534.58 MB | raw | 0 | |
| OMIX005581-32 | fecal pellet-negative ion mode-control2 | 16 | Metabolome Data by Mass Spectrometry (MS) | 550.04 MB | raw | 0 | |
| OMIX005581-33 | fecal pellet-negative ion mode-control3 | 16 | Metabolome Data by Mass Spectrometry (MS) | 537.32 MB | raw | 0 | |
| OMIX005581-34 | fecal pellet-negative ion mode-control4 | 16 | Metabolome Data by Mass Spectrometry (MS) | 536.58 MB | raw | 0 | |
| OMIX005581-35 | fecal pellet-negative ion mode-control5 | 16 | Metabolome Data by Mass Spectrometry (MS) | 547.19 MB | raw | 0 | |
| OMIX005581-36 | fecal pellet-negative ion mode-control6 | 16 | Metabolome Data by Mass Spectrometry (MS) | 533.09 MB | raw | 0 | |
| OMIX005581-37 | fecal pellet-negative ion mode-control7 | 16 | Metabolome Data by Mass Spectrometry (MS) | 525.08 MB | raw | 0 | |
| OMIX005581-38 | fecal pellet-negative ion mode-control8 | 16 | Metabolome Data by Mass Spectrometry (MS) | 533.76 MB | raw | 0 | |
| OMIX005581-39 | fecal pellet-negative ion mode-oxygen10 | 16 | Metabolome Data by Mass Spectrometry (MS) | 535.82 MB | raw | 0 | |
| OMIX005581-40 | fecal pellet-negative ion mode-oxygen11 | 16 | Metabolome Data by Mass Spectrometry (MS) | 543.64 MB | raw | 0 | |
| OMIX005581-41 | fecal pellet-negative ion mode-oxygen12 | 16 | Metabolome Data by Mass Spectrometry (MS) | 521.71 MB | raw | 0 | |
| OMIX005581-42 | fecal pellet-negative ion mode-oxygen13 | 16 | Metabolome Data by Mass Spectrometry (MS) | 520.63 MB | raw | 0 | |
| OMIX005581-43 | fecal pellet-negative ion mode-oxygen14 | 16 | Metabolome Data by Mass Spectrometry (MS) | 559.48 MB | raw | 0 | |
| OMIX005581-44 | fecal pellet-negative ion mode-oxygen15 | 16 | Metabolome Data by Mass Spectrometry (MS) | 541.45 MB | raw | 0 | |
| OMIX005581-45 | fecal pellet-negative ion mode-oxygen9 | 16 | Metabolome Data by Mass Spectrometry (MS) | 522.36 MB | raw | 0 | |
| OMIX005581-46 | fecal pellet-positive ion mode-control1 | 16 | Metabolome Data by Mass Spectrometry (MS) | 344.14 MB | raw | 0 | |
| OMIX005581-47 | fecal pellet-positive ion mode-control2 | 16 | Metabolome Data by Mass Spectrometry (MS) | 314.23 MB | raw | 0 | |
| OMIX005581-48 | fecal pellet-positive ion mode-control3 | 16 | Metabolome Data by Mass Spectrometry (MS) | 312.1 MB | raw | 0 | |
| OMIX005581-49 | fecal pellet-positive ion mode-control4 | 16 | Metabolome Data by Mass Spectrometry (MS) | 318.61 MB | raw | 0 | |
| OMIX005581-50 | fecal pellet-positive ion mode-control5 | 16 | Metabolome Data by Mass Spectrometry (MS) | 323.75 MB | raw | 0 | |
| OMIX005581-51 | fecal pellet-positive ion mode-control6 | 16 | Metabolome Data by Mass Spectrometry (MS) | 322.15 MB | raw | 0 | |
| OMIX005581-52 | fecal pellet-positive ion mode-control7 | 16 | Metabolome Data by Mass Spectrometry (MS) | 301.9 MB | raw | 0 | |
| OMIX005581-53 | fecal pellet-positive ion mode-control8 | 16 | Metabolome Data by Mass Spectrometry (MS) | 297.52 MB | raw | 0 | |
| OMIX005581-54 | fecal pellet- positive ion mode-oxygen10 | 16 | Metabolome Data by Mass Spectrometry (MS) | 353.69 MB | raw | 0 | |
| OMIX005581-55 | fecal pellet- positive ion mode-oxygen11 | 16 | Metabolome Data by Mass Spectrometry (MS) | 341.25 MB | raw | 0 | |
| OMIX005581-56 | fecal pellet- positive ion mode-oxygen12 | 16 | Metabolome Data by Mass Spectrometry (MS) | 288.54 MB | raw | 0 | |
| OMIX005581-57 | fecal pellet- positive ion mode-oxygen13 | 16 | Metabolome Data by Mass Spectrometry (MS) | 329.96 MB | raw | 0 | |
| OMIX005581-58 | fecal pellet- positive ion mode-oxygen14 | 16 | Metabolome Data by Mass Spectrometry (MS) | 348.75 MB | raw | 0 | |
| OMIX005581-59 | fecal pellet- positive ion mode-oxygen15 | 16 | Metabolome Data by Mass Spectrometry (MS) | 332.48 MB | raw | 0 | |
| OMIX005581-60 | fecal pellet- positive ion mode-oxygen9 | 16 | Metabolome Data by Mass Spectrometry (MS) | 296.89 MB | raw | 0 |