Single-cell sequencing reveals alterations in the PBMC landscape and monocyte status during colorectal adenocarcinoma formation
| Title | Single-cell sequencing reveals alterations in the PBMC landscape and monocyte status during colorectal adenocarcinoma formation |
|---|---|
| Description | We screened 5 healthy subjects, 5 adenoma patients and 5 early-stage adenocarcinoma patients who met the inclusion and exclusion criteria of endoscopic and pathological results. PBMC isolation and single-cell sequencing were performed using the peripheral blood from the patients. Further analysis was carried out on cell subsets. The PBMC scRNA-seq data were subjected to quality control. Expression of mitochondrial genes was concentrated in a certain area (less than 10% of the total number of genes) . After filtering of cells with a high mitochondrial gene ratio and a high erythrocyte gene ratio, a total of 110916 cells from 15 samples were analysed. |
| Organism | Homo sapiens |
| Data Type | Expression Profiling by NGS |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA021923 |
| Release Date | 2024-03-26 |
| Submitter | Jiasheng Xu (1821286450@qq.com) |
| Organization | The Second Affiliated Hospital, Zhejiang University School of Medicine |
| Submission Date | 2024-01-22 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX005724-01 | cytof-raw data | 3 | Expression Profiling by NGS | 46.8 MB | zip | 0 | Unavailable |