| Title | ATAC_seq of lung adenocarcinoma |
|---|---|
| Description | Lung adenocarcinoma, a prevalent sub type of lung cancer, serves as the focal point of our project. We meticulously collected specimens across various stages of lung adenocarcinoma development alongside control samples from conditions such as pneumonia and pulmonary fibrosis . Utilizing advanced genomic techniques, including Whole Genome Bisulfite Sequencing , Assay for Transposase-Accessible Chromatin sequencing , and RNA sequencing, we conducted comprehensive analyses on these specimens. Our approach enabled the creation of detailed epigenetic landscapes of lung adenocarcinoma at differing stages of its evolution. By integrating this with stage-specific expression profiles, we delved into the epigenetic underpinnings that drive the progression of lung adenocarcinoma, aiming to uncover novel insights into its pathogenesis. |
| Organism | Homo sapiens |
| Data Type | Chromatin Accessibility Profiling |
| Data Accessibility | Open-access |
| BioProject | PRJCA024580 |
| Release Date | 2025-02-26 |
| Submitter | Deqiang Sun (sund@gzhmu.edu.cn) |
| Organization | The Second Affiliated Hospital, Zhejiang University School of Medicine |
| Submission Date | 2024-04-03 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX006133-01 | ATAC_seq_2 | 11 | Chromatin Accessibility Profiling | 11.1 GB | zip | |
| OMIX006133-02 | ATAC_seq_1 | 11 | Chromatin Accessibility Profiling | 9.91 GB | zip |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Epigenetic-mediated positive feedback loop facilitates the progression of lung adenocarcinoma | iScience | 2025-10 | OMIX006134 OMIX006133 OMIX006132 | Deposit |