OMIX006304

1Summary
Title Single-cell profiling of the amphioxus digestive tract reveals conservation of endocrine cells in chordates
Description In this study, cells in the digestive tract of a cephalochordate, Branchiostoma floridae, were profiled using bulk-tissue and single-cell RNA-sequencing. Furthermore, Pdx, Ilp1, Ilp2, and Ilpr knockout amphioxus lines were investigated to study midgut development and Ilp function in detail.
Organism Branchiostoma floridae
Data Type Expression Profiling
Data Accessibility Open-access
BioProject PRJCA025534
Release Date 2024-12-09
Submitter Weiqiang Liu (weiqiang_liu2015@outlook.com)
Organization Institute of Zoology, Chinese Academy of Sciences
Submission Date 2024-04-24
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX006304-01 bulk-RNA-seq_scRNA-seq_amphioxus_digestive_tract.tar.gz 94 Expression Profiling 9.69 GB tar.gz
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
volutionary dynamics of FoxQ2 transcription factors across metazoans reveals three ancient paralogs Communications Biology 2025-12 OMIX006304 Secondary use
Single-cell profiling of the amphioxus digestive tract reveals conservation of endocrine cells in chordates Science Advances 2024-12 OMIX006304 Deposit

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