| Title | Single-cell transcriptome analysis reveals molecular subtypes and potential therapeutic targets of acute mixed phenotype leukemia |
|---|---|
| Description | To investigate leukemia cell heterogeneity in T/My MPAL, we conducted single-cell RNA sequencing on bone marrow samples from eight T/My MPAL, six AML, and three T-ALL patients, along with 23 normal controls, using the 10X Genomics platform. |
| Organism | Homo sapiens |
| Data Type | Expression Profiling |
| Data Accessibility | Open-access |
| BioProject | PRJCA027336 |
| Release Date | 2025-11-13 |
| Submitter | Wang Qianghu (wangqh@njmu.edu.cn) |
| Organization | Nanjing Medical University |
| Submission Date | 2024-06-23 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX006728-01 | single cell RNA sequencing data for Nomral21 | 1 | Expression Profiling | 22.37 MB | zip | |
| OMIX006728-02 | single cell RNA sequencing data for Normal22 | 1 | Expression Profiling | 11.33 MB | zip | |
| OMIX006728-03 | single cell RNA sequencing data for Normal23 | 1 | Expression Profiling | 35.69 MB | zip | |
| OMIX006728-04 | single cell RNA sequencing data for TALL1 | 1 | Expression Profiling | 95.28 MB | zip | |
| OMIX006728-05 | single cell RNA sequencing data for TALL2 | 1 | Expression Profiling | 82.46 MB | zip | |
| OMIX006728-06 | single cell RNA sequencing data for TALL3 | 1 | Expression Profiling | 123.16 MB | zip | |
| OMIX006728-07 | single cell RNA sequencing data for TMMPAL10 | 1 | Expression Profiling | 66.71 MB | zip | |
| OMIX006728-08 | single cell RNA sequencing data for TMMPAL5 | 1 | Expression Profiling | 56.38 MB | zip | |
| OMIX006728-09 | single cell RNA sequencing data for TMMPAL6 | 1 | Expression Profiling | 137.97 MB | zip | |
| OMIX006728-10 | single cell RNA sequencing data for TMMPAL7 | 1 | Expression Profiling | 118.15 MB | zip | |
| OMIX006728-11 | single cell RNA sequencing data for TMMPAL9 | 1 | Expression Profiling | 95.06 MB | zip |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Single-cell transcriptome analysis defines novel molecular subtypes and reveals therapeutic implications of T/myeloid mixed-phenotype acute leukemia | Genome Medicine | 2025-11 | OMIX006728 OMIX005014 OMIX002180 | Deposit |