Celastrol reduces cisplatin-induced nephrotoxicity in kidney organoids derived from human iPSCs
| Title | Celastrol reduces cisplatin-induced nephrotoxicity in kidney organoids derived from human iPSCs |
|---|---|
| Description | We investigated the ability of celastrol to reduce cisplatin-induced nephrotoxicity using kidney organoids. RNA-seq analyses were performed to determine the mechanisms of celastrol function in the kidney. Four groups of samples were conducted to be compared based on transcriptional level, including 50 μM cisplatin treated, 2 μM celastrol treated, 2 μM celastrol plus 50 μM cisplatin treated, and control samples. |
| Organism | Homo sapiens |
| Data Type | Expression Profiling by NGS |
| Data Accessibility | Open-access |
| BioProject | PRJCA028950 |
| Release Date | 2024-08-10 |
| Submitter | Qizheng Wang (wang_qizheng@gibh.ac.cn) |
| Organization | Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences |
| Submission Date | 2024-08-08 |
The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX007089-01 | BulkRNAseq_genecount_for_Submit | 12 | Expression Profiling by NGS | 1.5 MB | csv | 0 | Unavailable |