OMIX007371

1Summary
Title Untarget metabolomics of crizotinib-induced hepatotoxicity
Description Crizotinib's hepatotoxicity is associated with metabolism abnormality and this study aims to uncover the underlying alteration of metabolites.
Organism Mus musculus
Data Type Metabolome Data by Mass Spectrometry (MS)
Data Accessibility Open-access
BioProject PRJCA030133
Release Date 2025-02-01
Submitter xiangliang huang (huangxiangliang@zju.edu.cn)
Organization Zhejiang University
Submission Date 2024-09-12
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX007371-01 negative and positive ions model for detection of metabolites distribution in NC + ctrl; NC + crizo; shSqle + ctrl; shSqle +crizo 128 Metabolome Data by Mass Spectrometry (MS) 2.29 GB tar.gz
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
Disturbing Cholesterol/Sphingolipid Metabolism by Squalene Epoxidase Arises Crizotinib Hepatotoxicity Advanced Science 2025-01 OMIX007371 Deposit

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