| Title | Proteome dataset of chromatin-associated proteins by Hi-MS in MDA-MB-231 cells |
|---|---|
| Description | MDA-MB-231 breast cancer cells were pre-treated with or without 10% 1,6-hexanediol (HEX) for 10 min, cross-linked using 1% formaldehyde, and digested with Hae III. Biotinylated bridge linkers were ligated to the DNA fragment ends, and after sonication, biotinylated linker/DNA/protein complexes were captured with magnetic streptavidin beads for label-free quantitative mass spectrometry analysis. |
| Organism | Homo sapiens |
| Data Type | Proteomic Data by Mass Spectrometry (MS) |
| Data Accessibility | Open-access |
| BioProject | PRJCA017309 |
| Release Date | 2024-10-05 |
| Submitter | Zhang Long (l_zhang@zju.edu.cn) |
| Organization | Life Sciences Institute, Zhejiang University |
| Submission Date | 2024-10-03 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX007562-01 | mass spectrometry for chromatin-associated proteins in MDA-MB-231 cells | 1 | Proteomic Data by Mass Spectrometry (MS) | 975.87 MB | raw | |
| OMIX007562-02 | mass spectrometry for chromatin-associated proteins in MDA-MB-231 cells | 1 | Proteomic Data by Mass Spectrometry (MS) | 977.26 MB | raw | |
| OMIX007562-03 | mass spectrometry for chromatin-associated proteins in MDA-MB-231 cells | 1 | Proteomic Data by Mass Spectrometry (MS) | 976.14 MB | raw | |
| OMIX007562-04 | mass spectrometry for chromatin-associated proteins in MDA-MB-231 cells treated with 1,6-HD | 1 | Proteomic Data by Mass Spectrometry (MS) | 638.88 MB | raw | |
| OMIX007562-05 | mass spectrometry for chromatin-associated proteins in MDA-MB-231 cells treated with 1,6-HD-2 | 1 | Proteomic Data by Mass Spectrometry (MS) | 654.73 MB | raw | |
| OMIX007562-06 | mass spectrometry for chromatin-associated proteins in MDA-MB-231 cells treated with 1,6-HD-3 | 1 | Proteomic Data by Mass Spectrometry (MS) | 587.3 MB | raw |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Targeting FOXM1 condensates reduces breast tumour growth and metastasis | Nature | 2025-01 | OMIX007561 OMIX007562 | Deposit |