Integrated analysis of metabolome and microbiome in a rat model of perimenopausal syndrome
| Title | Integrated analysis of metabolome and microbiome in a rat model of perimenopausal syndrome |
|---|---|
| Description | To examine the disparities in serum and intestinal tissue metabolites between a perimenopausal rat model and control rats, and to analyze the diversity and functionality of intestinal microorganisms to determine potential correlation between intestinal flora and metabolites. We established a rat model of perimenopausal syndrome (PMS) and performed an integrated analysis of metabolome and microbiome. The findings of this study are expected to contribute to understanding the indications and contraindications for estrogen application in perimenopausal women and to aid in the development of appropriate therapeutic agents. |
| Organism | Mus musculus |
| Data Type | Metabolome Data by Mass Spectrometry (MS) |
| Data Accessibility | Open-access |
| BioProject | PRJCA031086 |
| Release Date | 2024-10-15 |
| Submitter | Xiujuan Cui (drcuixj@163.com) |
| Organization | Tengzhou Central People's Hospital |
| Submission Date | 2024-10-14 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX007622-01 | NEG_Gg20BAJ_Intestinal_Control_1.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 77.1 MB | raw | 0 | |
| OMIX007622-02 | NEG_Gg20BAJ_Intestinal_Control_2.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 76.91 MB | raw | 0 | |
| OMIX007622-03 | NEG_Gg20BAJ_Intestinal_Control_3.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 83.71 MB | raw | 0 | |
| OMIX007622-04 | NEG_Gg20BAJ_Intestinal_Control_4.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 77.45 MB | raw | 0 | |
| OMIX007622-05 | NEG_Gg20BAJ_Intestinal_Control_5.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 76.85 MB | raw | 0 | |
| OMIX007622-06 | NEG_Gg20BAJ_Intestinal_Control_6.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 77.85 MB | raw | 0 | |
| OMIX007622-07 | NEG_Gg20BAJ_Intestinal_Model_1.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 77.38 MB | raw | 0 | |
| OMIX007622-08 | NEG_Gg20BAJ_Intestinal_Model_2.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 77.6 MB | raw | 0 | |
| OMIX007622-09 | NEG_Gg20BAJ_Intestinal_Model_3.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 77.44 MB | raw | 0 | |
| OMIX007622-10 | NEG_Gg20BAJ_Intestinal_Model_4.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 77.3 MB | raw | 0 | |
| OMIX007622-11 | NEG_Gg20BAJ_Intestinal_Model_5.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 77.63 MB | raw | 0 | |
| OMIX007622-12 | NEG_Gg20BAJ_Intestinal_Model_6.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 77.72 MB | raw | 0 | |
| OMIX007622-13 | NEG_Gg20BAJ_Intestinal_QC_1.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 78.45 MB | raw | 0 | |
| OMIX007622-14 | NEG_Gg20BAJ_Intestinal_QC_2.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 78.29 MB | raw | 0 | |
| OMIX007622-15 | NEG_Gg20BAJ_Intestinal_QC_3.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 78.72 MB | raw | 0 | |
| OMIX007622-16 | NEG_Gg20BAJ_Serum_Control_1.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 94.85 MB | raw | 0 | |
| OMIX007622-17 | NEG_Gg20BAJ_Serum_Control_2.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 95.22 MB | raw | 0 | |
| OMIX007622-18 | NEG_Gg20BAJ_Serum_Control_3.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 96.58 MB | raw | 0 | |
| OMIX007622-19 | NEG_Gg20BAJ_Serum_Control_4.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 96.52 MB | raw | 0 | |
| OMIX007622-20 | NEG_Gg20BAJ_Serum_Control_5.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 96.42 MB | raw | 0 | |
| OMIX007622-21 | NEG_Gg20BAJ_Serum_Control_6.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 97.64 MB | raw | 0 | |
| OMIX007622-22 | NEG_Gg20BAJ_Serum_Model_1.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 95.88 MB | raw | 0 | |
| OMIX007622-23 | NEG_Gg20BAJ_Serum_Model_2.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 96.08 MB | raw | 0 | |
| OMIX007622-24 | NEG_Gg20BAJ_Serum_Model_3.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 96.33 MB | raw | 0 | |
| OMIX007622-25 | NEG_Gg20BAJ_Serum_Model_4.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 95.64 MB | raw | 0 | |
| OMIX007622-26 | NEG_Gg20BAJ_Serum_Model_5.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 92.03 MB | raw | 0 | |
| OMIX007622-27 | NEG_Gg20BAJ_Serum_Model_6.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 94.52 MB | raw | 0 | |
| OMIX007622-28 | NEG_Gg20BAJ_Serum_QC_1.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 95.98 MB | raw | 0 | |
| OMIX007622-29 | NEG_Gg20BAJ_Serum_QC_2.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 96.26 MB | raw | 0 | |
| OMIX007622-30 | NEG_Gg20BAJ_Serum_QC_3.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 95.66 MB | raw | 0 | |
| OMIX007622-31 | POS_Gg20BAJ_Intestinal_Control_1.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 81.99 MB | raw | 0 | |
| OMIX007622-32 | POS_Gg20BAJ_Intestinal_Control_2.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 82.87 MB | raw | 0 | |
| OMIX007622-33 | POS_Gg20BAJ_Intestinal_Control_3.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 92.2 MB | raw | 0 | |
| OMIX007622-34 | POS_Gg20BAJ_Intestinal_Control_4.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 83.65 MB | raw | 0 | |
| OMIX007622-35 | POS_Gg20BAJ_Intestinal_Control_5.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 82.93 MB | raw | 0 | |
| OMIX007622-36 | POS_Gg20BAJ_Intestinal_Control_6.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 82.7 MB | raw | 0 | |
| OMIX007622-37 | POS_Gg20BAJ_Intestinal_Model_1.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 83.28 MB | raw | 0 | |
| OMIX007622-38 | POS_Gg20BAJ_Intestinal_Model_2.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 82.6 MB | raw | 0 | |
| OMIX007622-39 | POS_Gg20BAJ_Intestinal_Model_3.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 82.7 MB | raw | 0 | |
| OMIX007622-40 | POS_Gg20BAJ_Intestinal_Model_4.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 82.42 MB | raw | 0 | |
| OMIX007622-41 | POS_Gg20BAJ_Intestinal_Model_5.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 83.47 MB | raw | 0 | |
| OMIX007622-42 | POS_Gg20BAJ_Intestinal_Model_6.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 82.21 MB | raw | 0 | |
| OMIX007622-43 | POS_Gg20BAJ_Intestinal_QC_1.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 83.12 MB | raw | 0 | |
| OMIX007622-44 | POS_Gg20BAJ_Intestinal_QC_2.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 83.08 MB | raw | 0 | |
| OMIX007622-45 | POS_Gg20BAJ_Intestinal_QC_3.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 82.87 MB | raw | 0 | |
| OMIX007622-46 | POS_Gg20BAJ_Serum_Control_1.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 87.85 MB | raw | 0 | |
| OMIX007622-47 | POS_Gg20BAJ_Serum_Control_2.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 88.8 MB | raw | 0 | |
| OMIX007622-48 | POS_Gg20BAJ_Serum_Control_3.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 88.22 MB | raw | 0 | |
| OMIX007622-49 | POS_Gg20BAJ_Serum_Control_4.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 88.46 MB | raw | 0 | |
| OMIX007622-50 | POS_Gg20BAJ_Serum_Control_5.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 88.09 MB | raw | 0 | |
| OMIX007622-51 | POS_Gg20BAJ_Serum_Control_6.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 88.44 MB | raw | 0 | |
| OMIX007622-52 | POS_Gg20BAJ_Serum_Model_1.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 88.85 MB | raw | 0 | |
| OMIX007622-53 | POS_Gg20BAJ_Serum_Model_2.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 88.42 MB | raw | 0 | |
| OMIX007622-54 | POS_Gg20BAJ_Serum_Model_3.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 88.34 MB | raw | 0 | |
| OMIX007622-55 | POS_Gg20BAJ_Serum_Model_4.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 87.96 MB | raw | 0 | |
| OMIX007622-56 | POS_Gg20BAJ_Serum_Model_5.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 88.27 MB | raw | 0 | |
| OMIX007622-57 | POS_Gg20BAJ_Serum_Model_6.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 88.16 MB | raw | 0 | |
| OMIX007622-58 | POS_Gg20BAJ_Serum_QC_1.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 88.42 MB | raw | 0 | |
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| OMIX007622-60 | POS_Gg20BAJ_Serum_QC_3.raw | 1 | Metabolome Data by Mass Spectrometry (MS) | 88.17 MB | raw | 0 |