OMIX

Enhanced Myofibroblast Differentiation of eMSCs in Intrauterine Adhesions

OMIX008020

1Summary
Title Enhanced Myofibroblast Differentiation of eMSCs in Intrauterine Adhesions
Description Intrauterine adhesions (IUA) is one of the most common gynecological diseases and main causes of uterine infertility. Among proposed hypotheses on IUA development, the reduced endometrial regeneration resulting from loss of functional stem cells has been proposed as the key factor affecting the IUA prognosis. However, the underlying mechanisms mostly remain unclear. Because the eMSCs (endometrial mesenchymal stem/stromal cells) play a critical role in both supporting the gland development and also preparing the environment for embryo implantation through decidualization, the characteristics and functions were compared between the eMSCs derived from IUA and non-IUA patients, to uncover the important roles of eMSCs in IUA and also the underlying mechanisms.
Organism Homo sapiens
Data Type Expression Profiling by Array
Data Accessibility Open-access
BioProject PRJCA032869
Release Date 2024-11-28
Submitter Jianyong Xu (xujianyong820915@163.com)
Organization Shenzhen Zhongshan Obstetrics and Gynecology Hospital
Submission Date 2024-11-27
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download Times Download
OMIX008020-01 eMSC from IUA 1 Expression Profiling by Array 304.9 MB xls 0 Unavailable

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