| Title |
Gut microbe-derived betulinic acid alleviates sepsis-induced acute liver injury |
| Description |
The male C57BL/6J mice were housed under conditions of ad libitum access to food and water. The induction of polymicrobial sepsis was achieved using the cecal ligation and puncture (CLP) method, as described previously . In brief, the mice were initially administered anesthesia before CLP treatment by ligating and puncturing their cecum twice using an 18 G needle. The survival rate was observed every hour during the first 48-hour period. For exercise training, mice were randomly assigned to two activity groups: exercise training (Exe) or sedentary control (Ctrl). The Exe mice underwent a treadmill exercise routine as described previously, starting at 5 meters (m) per minute for 10 minutes and then increasing to 15 m per minute for 60 minutes once daily for 14 days. |
| Organism |
Mus musculus |
| Data Type |
Metabolome Data by Mass Spectrometry (MS) |
| Data Accessibility |
Open-access |
| BioProject |
PRJCA035256 |
| Release Date |
2025-01-22 |
| Submitter |
Wei Huang (wei11920012@163.com) |
| Organization |
Southern Medical University |
| Submission Date |
2025-01-18 |