OMIX008930

1Summary

Title	Single-cell and spatial RNA sequencing identify divergent microenvironments and progression signatures in early- versus late-onset prostate cancer
Description	This dataset consists of matrices of single-cell RNA sequencing from 20 prostate cancer tissues, and of spatial transcriptomic sequencing from 4 prostate cancer tissues, emphasising the differences of tumour microenvironment associated with age-of onset.
Organism	Homo sapiens
Data Type	Expression Profiling
Data Accessibility	Open-access
BioProject	PRJCA035793
Release Date	2025-07-04
Submitter	Meilin Wang (mwang@njmu.edu.cn)
Organization	Nanjing Medical University
Submission Date	2025-02-07

2Files & Download

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File ID	File Title	Number/Samples	File Type	File Size	File Suffix	Download
OMIX008930-01	EOPC Sample 1 - Discovery scRNA-seq	1	Expression Profiling	116 MB	tar.gz	FTP HTTPs
OMIX008930-02	EOPC Sample 2 - Discovery scRNA-seq	1	Expression Profiling	88.69 MB	tar.gz	FTP HTTPs
OMIX008930-03	EOPC Sample 3 - Discovery scRNA-seq	1	Expression Profiling	78.18 MB	tar.gz	FTP HTTPs
OMIX008930-04	EOPC Sample 4 - Discovery scRNA-seq	1	Expression Profiling	82.37 MB	tar.gz	FTP HTTPs
OMIX008930-05	EOPC Sample 4 - Discovery ST-seq	1	Expression Profiling	16.17 MB	tar.gz	FTP HTTPs
OMIX008930-06	LOPC Sample 1 - Discovery scRNA-seq	1	Expression Profiling	66.25 MB	tar.gz	FTP HTTPs
OMIX008930-07	LOPC Sample 2 - Discovery scRNA-seq	1	Expression Profiling	83.72 MB	tar.gz	FTP HTTPs
OMIX008930-08	LOPC Sample 3 - Discovery scRNA-seq	1	Expression Profiling	73.94 MB	tar.gz	FTP HTTPs
OMIX008930-09	LOPC Sample 3 - Discovery ST-seq	1	Expression Profiling	22.51 MB	tar.gz	FTP HTTPs
OMIX008930-10	LOPC Sample 4 - Discovery scRNA-seq	1	Expression Profiling	44.75 MB	tar.gz	FTP HTTPs
OMIX008930-11	LOPC Sample 5 - Discovery scRNA-seq	1	Expression Profiling	84.63 MB	tar.gz	FTP HTTPs
OMIX008930-12	LOPC Sample 6 - Discovery scRNA-seq	1	Expression Profiling	61.81 MB	tar.gz	FTP HTTPs
OMIX008930-13	EOPC Sample 1 - Validation scRNA-seq	1	Expression Profiling	104.03 MB	tar.gz	FTP HTTPs
OMIX008930-14	EOPC Sample 2 - Validation scRNA-seq	1	Expression Profiling	78.53 MB	tar.gz	FTP HTTPs
OMIX008930-15	EOPC Sample 3 - Validation scRNA-seq	1	Expression Profiling	63.29 MB	tar.gz	FTP HTTPs
OMIX008930-16	EOPC Sample 4 - Validation scRNA-seq	1	Expression Profiling	73.12 MB	tar.gz	FTP HTTPs
OMIX008930-17	EOPC Sample 4 - Validation ST-seq	1	Expression Profiling	17.83 MB	tar.gz	FTP HTTPs
OMIX008930-18	EOPC Sample 5 - Validation scRNA-seq	1	Expression Profiling	79.42 MB	tar.gz	FTP HTTPs
OMIX008930-19	LOPC Sample 1 - Validation scRNA-seq	1	Expression Profiling	78.38 MB	tar.gz	FTP HTTPs
OMIX008930-20	LOPC Sample 1 - Validation ST-seq	1	Expression Profiling	10.89 MB	tar.gz	FTP HTTPs
OMIX008930-21	LOPC Sample 2 - Validation scRNA-seq	1	Expression Profiling	74.26 MB	tar.gz	FTP HTTPs
OMIX008930-22	LOPC Sample 3 - Validation scRNA-seq	1	Expression Profiling	63.57 MB	tar.gz	FTP HTTPs
OMIX008930-23	LOPC Sample 4 - Validation scRNA-seq	1	Expression Profiling	80.44 MB	tar.gz	FTP HTTPs
OMIX008930-24	LOPC Sample 5 - Validation scRNA-seq	1	Expression Profiling	76.04 MB	tar.gz	FTP HTTPs

3Relevant Publications

Paper Title	Journal Name	Publish Time	Accession	Citing Type
Analysis of the transcriptomic and metabolomic landscape of prostate cancer with different anatomical origins using snFLARE-seq and mxFRIZNGRND	Nature Communications	2026-02	OMIX013310 OMIX013309 OMIX008930	Deposit
Single-cell and spatial RNA sequencing identify divergent microenvironments and progression signatures in early-versus late-onset prostate cancer	Nature Aging	2025-04	OMIX008930	Deposit

Registration number	2025BAT00320
Backup number	BF2025020816251