| Title | Immune properties of patients with acute HBV infection |
|---|---|
| Description | we conducted scRNA-seq on peripheral blood mononuclear cells (PBMCs) from five patients with acute HBV infection (AHB) and five healthy donors (HD). This allowed us to examine the transcriptomic profiles of these cells and their T cell receptor (TCR) repertoires. Concurrently, we analyzed immune cells from a liver biopsy of one patient. By employing anchoring integration and unsupervised clustering, we identified 36 unique cell types and states (subsets) in a pool of 49,305 high-quality single cells, based on their distinct signature markers of gene expression |
| Organism | Homo sapiens |
| Data Type | Expression Profiling |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA010340 |
| Release Date | 2025-04-27 |
| Submitter | Jianhua Li (jianhuali@fudan.edu.cn) |
| Organization | Fudan University |
| Submission Date | 2025-03-20 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX009529-01 | AHB1_RNA | 1 | Expression Profiling | 5.9 MB | csv.tar.gz | Controlled |
| OMIX009529-02 | AHB1_TCR | 1 | Expression Profiling | 246.94 KB | csv.tar.gz | Controlled |
| OMIX009529-03 | AHB2_RNA | 1 | Expression Profiling | 5.76 MB | csv.tar.gz | Controlled |
| OMIX009529-04 | AHB2_TCR | 1 | Expression Profiling | 271.45 KB | csv.tar.gz | Controlled |
| OMIX009529-05 | AHB3_L_RNA | 1 | Expression Profiling | 26.89 MB | csv.tar.gz | Controlled |
| OMIX009529-06 | AHB3_L_TCR | 1 | Expression Profiling | 527.33 KB | csv.tar.gz | Controlled |
| OMIX009529-07 | AHB3_RNA | 1 | Expression Profiling | 8.85 MB | csv.tar.gz | Controlled |
| OMIX009529-08 | AHB3_TCR | 1 | Expression Profiling | 452.81 KB | csv.tar.gz | Controlled |
| OMIX009529-09 | AHB4_RNA | 1 | Expression Profiling | 10.01 MB | csv.tar.gz | Controlled |
| OMIX009529-10 | AHB4_TCR | 1 | Expression Profiling | 530.64 KB | csv.tar.gz | Controlled |
| OMIX009529-11 | AHB5_RNA | 1 | Expression Profiling | 9.9 MB | csv.tar.gz | Controlled |
| OMIX009529-12 | AHB5_TCR | 1 | Expression Profiling | 636.46 KB | csv.tar.gz | Controlled |
| OMIX009529-13 | HD1_RNA | 1 | Expression Profiling | 6.51 MB | csv.tar.gz | Controlled |
| OMIX009529-14 | HD1_TCR | 1 | Expression Profiling | 208.76 KB | csv.tar.gz | Controlled |
| OMIX009529-15 | HD2_RNA | 1 | Expression Profiling | 3.75 MB | csv.tar.gz | Controlled |
| OMIX009529-16 | HD2_TCR | 1 | Expression Profiling | 84.07 KB | csv.tar.gz | Controlled |
| OMIX009529-17 | HD3_RNA | 1 | Expression Profiling | 2.35 MB | csv.tar.gz | Controlled |
| OMIX009529-18 | HD3_TCR | 1 | Expression Profiling | 74.25 KB | csv.tar.gz | Controlled |
| OMIX009529-19 | HD4_RNA | 1 | Expression Profiling | 8.2 MB | csv.tar.gz | Controlled |
| OMIX009529-20 | HD4_TCR | 1 | Expression Profiling | 280.88 KB | csv.tar.gz | Controlled |
| OMIX009529-21 | HD5_RNA | 1 | Expression Profiling | 9.89 MB | csv.tar.gz | Controlled |
| OMIX009529-22 | HD5_TCR | 1 | Expression Profiling | 694.76 KB | csv.tar.gz | Controlled |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Hepatitis B virus surface antigen drives T cell immunity through non-canonical antigen presentation in mice | Nature Communications | 2025-05 | OMIX009529 | Deposit |