OMIX010115

1Summary
Title Intermittent fasting exacerbates colon inflammation by promoting Th17 cell differentiation through inhibition of gut microbiota-derived Indoleacrylic acid
Description Prepare fecal samples randomly for analysis. Process data using SubstraTIQ QI software with parameters set to a precursor tolerance of 5 ppm, product tolerance of 10 ppm, and a production threshold of 5%. Identify compounds by comparing with databases such as HMDB, LipidMap , and Metlin. Construct positive and negative ion mode data matrices, import into R software for principal component analysis to evaluate sample distribution and analysis stability. Further use OPLS-DA and PLS-DA to identify group differences in metabolites.
Organism Mus
Data Type Metabolome Data by Mass Spectrometry (MS)
Data Accessibility Open-access
BioProject PRJCA039957
Release Date 2025-05-10
Submitter Rui fu (18949236732@163.com)
Organization First Affiliated Hospital of Anhui Medical University
Submission Date 2025-05-09
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX010115-01 raw data 24 Metabolome Data by Mass Spectrometry (MS) 3.12 GB zip
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
Intermittent fasting exacerbates colon inflammation by promoting Th17 cell differentiation through inhibition of gut microbiota-derived indoleacrylic acid World Journal of Gastroenterology 2025-06 OMIX010115 Deposit

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