| Title |
Screen potential marker proteins influencing spermatogenesis in the testes of Shandong Black Cattle bulls via multi-omics integrated analysis. |
| Description |
Testes tissue was collected from 8 12-month-old Shandong black cattle. Testes were divided into two groups according to the morphological characteristics of testes: group 1 (weight > 120 g) and group 2 (weight < 120 g). With group 2 as the control group, protein and metabolite libraries were constructed for joint analysis, and candidate marker proteins affecting testes growth and development were screened. It provides some theoretical basis for testes growth and development and selection of bulls. The results revealed that 1553 differential proteins (DEPs) were differentially expressed between the large and small testes of Black Bleykett bulls, with 1219 being upregulated and 334 being downregulated. Metabolomics demonstrated that 59 upregulated metabolites were enriched in the glucose metabolism pathway (uridine diphosphate glucose), and 14 downregulated metabolites were significantly enriched in metabolic pathways (hypoxanthine). |
| Organism |
Bos taurus |
| Data Type |
Metabolome Data by Mass Spectrometry (MS) |
| Data Accessibility |
Open-access |
| BioProject |
PRJCA041438 |
| Release Date |
2025-06-12 |
| Submitter |
YA JUAN DONG (etcenter@126.com) |
| Organization |
Qingdao Agricultural University |
| Submission Date |
2025-06-11 |