OMIX010642

1Summary
Title RNA-seq analysis between KRAS-amplified and non-amplified colorectal cancer (CRC) tissue samples
Description This dataset contains differentially expressed genes (DEGs) identified by RNA-seq analysis between KRAS-amplified and non-amplified colorectal cancer (CRC) tissue samples. A total of eight CRC samples (n=4 per group) were analyzed to explore the transcriptional differences associated with KRAS copy number status. Gene expression was quantified and DEGs were identified using DESeq2. The table includes gene symbols, log2 fold changes, adjusted p-values, and expression levels. This dataset supports the investigation of KRAS amplification-related molecular changes in CRC
Organism Homo sapiens
Data Type Expression Profiling
Data Accessibility Open-access
BioProject PRJCA041858
Release Date 2025-08-29
Submitter Xuanhua Yang (yangxh73@mail2.sysu.edu.cn)
Organization The Sixth Affiliated Hospital, Sun Yat-sen University
Submission Date 2025-06-18
2Files & Download

The data cannot be downloaded as it has not yet been registered in the Human Genetic Resource Management Platform of MOST.

File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX010642-01 RNA-seq analysis between KRAS-amplified and non-amplified colorectal cancer (CRC) tissue samples 1 Expression Profiling 2.7 MB xlsx Unavailable
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
KRAS amplification in colorectal cancer: correlations with clinicopathological features and prognosis in patients and prediction of response to targeted therapy Journal of Translational Medicine 2025-07 OMIX010642 Deposit

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