OMIX010698

1Summary
Title Metabolomic profiling of choline-to-TMA conversion by cultured gut microbes
Description Phocaeicola massiliensis, Veillonella spp., and Klebsiella pneumoniae were isolated from the feces of healthy individuals and cultured anaerobically in BHI medium supplemented with 1% choline chloride. Each strain was incubated at 37°C for 24 h. Culture supernatants were collected, and TMA levels were quantified using LC-MS/MS with d9-TMA as internal standard. This dataset characterizes the strain-specific ability of gut microbes to convert choline into TMA.
Organism Bacteria
Data Type Metabolome Data by Mass Spectrometry (MS)
Data Accessibility Open-access
BioProject PRJCA041981
Release Date 2025-06-22
Submitter Shuo Wang (mywanuo@163.com)
Organization Southern Medical University, Zhujiang hospital
Submission Date 2025-06-21
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX010698-01 microbe_choline_TMA.txt 9 Metabolome Data by Mass Spectrometry (MS) 279 bytes txt
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
Trimethylamine-N-oxide disrupts spermatogenesis by inducing mitochondrial oxidative stress injury through Hippo signaling Free Radical Biology & Medicine 2025-11 OMIX010698 Deposit

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