| Title | Single cell transcriptome profiling of peripheral blood cells in kidney transplant recipients with different rejection responses and treatments |
|---|---|
| Description | We present a single-cell RNA sequencing (scRNA-seq) dataset of peripheral blood mononuclear cells (PBMCs) obtained from kidney transplant recipients exhibiting distinct rejection types and treatment phases. Samples were collected both before and after targeted immunosuppressive therapy from recipients with T cell-mediated rejection (TCMR) and antibody-mediated rejection (ABMR), while samples from recipients with stable graft function and normal renal status were collected without intervention. |
| Organism | Homo sapiens |
| Data Type | Expression Profiling |
| Data Accessibility | Open-access |
| BioProject | PRJCA044608 |
| Release Date | 2025-12-01 |
| Submitter | Xuebin Wang (binxuewang@sjtu.edu.cn) |
| Organization | Shanghai Children's hospital |
| Submission Date | 2025-10-16 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX012347-01 | TCMR_1_pre | 1 | Expression Profiling | 129.68 MB | zip | |
| OMIX012347-02 | Normal_2 | 1 | Expression Profiling | 89.77 MB | zip | |
| OMIX012347-03 | ABMR_1_pre | 1 | Expression Profiling | 102.9 MB | zip | |
| OMIX012347-04 | TCMR_1_post | 1 | Expression Profiling | 117.91 MB | zip | |
| OMIX012347-05 | ABMR_1_post | 1 | Expression Profiling | 90.3 MB | zip | |
| OMIX012347-06 | Normal_1 | 1 | Expression Profiling | 100.66 MB | zip | |
| OMIX012347-07 | ABMR_2_pre | 1 | Expression Profiling | 156.78 MB | zip | |
| OMIX012347-08 | ABMR_2_post | 1 | Expression Profiling | 97.11 MB | zip |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| ScRNA profiling of peripheral blood in kidney transplant recipients across rejection responses and treatments | Scientific Data | 2025-12 | OMIX012347 | Deposit |