| Title | CD177+ Neutrophil-Platelet Aggregates Contribute to thromboinflammation via NETs in Necrotizing Enterocolitis |
|---|---|
| Description | Single-cell RNA sequencing was performed on intestinal tissue obtained from stage II+ necrotizing enterocolitis (NEC) patients undergoing surgical resection and from non-inflamed surgical controls (e.g., intestinal duplication). The immune-cell landscape of the bowel wall was mapped, with particular emphasis on the composition and heterogeneity of tissue-resident neutrophils. |
| Organism | Homo sapiens |
| Data Type | Expression Profiling |
| Data Accessibility | Controlled-access |
| BioProject | PRJCA048543 |
| Release Date | 2026-03-23 |
| Submitter | Yufeng Liu (eyyufengliu@scut.edu.cn) |
| Organization | South China University of Technology |
| Submission Date | 2025-10-19 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX012413-01 | NEC subject 1 intestine scRNA-seq | 1 | Expression Profiling | 104.41 MB | tar.gz | Controlled |
| OMIX012413-02 | NEC subject 2 intestine scRNA-seq | 1 | Expression Profiling | 74.11 MB | tar.gz | Controlled |
| OMIX012413-03 | NEC subject 3 intestine scRNA-seq | 1 | Expression Profiling | 128.79 MB | tar.gz | Controlled |
| OMIX012413-04 | Control subject 1 intestine scRNA-seq | 1 | Expression Profiling | 126.79 MB | tar.gz | Controlled |
| OMIX012413-05 | Control subject 2 intestine scRNA-seq | 1 | Expression Profiling | 112.99 MB | tar.gz | Controlled |
| OMIX012413-06 | Control subject 3 intestine scRNA-seq | 1 | Expression Profiling | 97.7 MB | tar.gz | Controlled |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| CD177⁺ neutrophil-platelet aggregates contribute to thromboinflammation via NETs in necrotizing enterocolitis | Nature Communications | 2026-03 | OMIX012457 OMIX012413 OMIX008000 | Deposit |