OMIX013654

1Summary
Title The Metabolomics Profiling of Primary Aldosteronism
Description Primary aldosteronism (PA), characterized by overt renin-independent aldosterone production, is the most common form endocrine hypertension. Compared with blood pressure-matched cases of essential hypertension (EH), PA is associated with a higher risk of cardiovascular morbidity and mortality. It is estimated that PA affects at least 10% of hypertensive patients and up to 25% of treatment-resistant hypertension. The screening, confirmatory testing, and subtype differentiation of PA for therapeutic management is a multi-step and complex process, resulting in low screening rates and poor clinical recognition. PA is an independent risk factor for metabolic morbidity. Metabolomic profiling is a relatively new strategy for the diagnosis and prognosis of disease through identification and quantification of various metabolites. In the current study, we aimed to investigate the potential biomakers for discriminating PA from EH, as well as subtype classification for PA, by untargeted metabolomics.
Organism Homo sapiens
Data Type Metabolome Data by Mass Spectrometry (MS)
Data Accessibility Controlled-access
BioProject PRJCA053420
Release Date 2026-01-10
Submitter Mei You (1448645208@qq.com)
Organization Army Medical University
Submission Date 2025-12-11
Request for this Data
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download
OMIX013654-03 BPA18 18 Metabolome Data by Mass Spectrometry (MS) 167.61 MB raw Controlled
OMIX013654-04 BPA19 19 Metabolome Data by Mass Spectrometry (MS) 169.97 MB raw Controlled
OMIX013654-05 BPA20 20 Metabolome Data by Mass Spectrometry (MS) 168.05 MB raw Controlled
OMIX013654-06 BPA21 21 Metabolome Data by Mass Spectrometry (MS) 171.29 MB raw Controlled
OMIX013654-07 BPA22 22 Metabolome Data by Mass Spectrometry (MS) 170.45 MB raw Controlled
OMIX013654-08 BPA23 23 Metabolome Data by Mass Spectrometry (MS) 170.11 MB raw Controlled
OMIX013654-09 BPA24 24 Metabolome Data by Mass Spectrometry (MS) 170.63 MB raw Controlled
OMIX013654-10 BPA25 25 Metabolome Data by Mass Spectrometry (MS) 172.2 MB raw Controlled
OMIX013654-11 BPA26 26 Metabolome Data by Mass Spectrometry (MS) 171.68 MB raw Controlled
OMIX013654-12 BPA27 27 Metabolome Data by Mass Spectrometry (MS) 171.27 MB raw Controlled
OMIX013654-13 BPA28 28 Metabolome Data by Mass Spectrometry (MS) 170.56 MB raw Controlled
OMIX013654-14 BPA29 29 Metabolome Data by Mass Spectrometry (MS) 172.53 MB raw Controlled
OMIX013654-15 BPA30 30 Metabolome Data by Mass Spectrometry (MS) 170.12 MB raw Controlled
OMIX013654-16 BPA31 31 Metabolome Data by Mass Spectrometry (MS) 169.37 MB raw Controlled
OMIX013654-17 BPA33 33 Metabolome Data by Mass Spectrometry (MS) 170.21 MB raw Controlled
OMIX013654-18 BPA32 32 Metabolome Data by Mass Spectrometry (MS) 168.89 MB raw Controlled
OMIX013654-19 BPA35 35 Metabolome Data by Mass Spectrometry (MS) 171.16 MB raw Controlled
OMIX013654-20 BPA34 34 Metabolome Data by Mass Spectrometry (MS) 169.93 MB raw Controlled
OMIX013654-21 BPA36 36 Metabolome Data by Mass Spectrometry (MS) 170.15 MB raw Controlled
OMIX013654-22 BPA37 37 Metabolome Data by Mass Spectrometry (MS) 171.82 MB raw Controlled
OMIX013654-23 EH2 39 Metabolome Data by Mass Spectrometry (MS) 176.68 MB raw Controlled
OMIX013654-24 EH1 38 Metabolome Data by Mass Spectrometry (MS) 170.06 MB raw Controlled
OMIX013654-25 EH3 40 Metabolome Data by Mass Spectrometry (MS) 169.1 MB raw Controlled
OMIX013654-26 EH4 41 Metabolome Data by Mass Spectrometry (MS) 167.64 MB raw Controlled
OMIX013654-27 EH5 42 Metabolome Data by Mass Spectrometry (MS) 169.15 MB raw Controlled
OMIX013654-28 EH6 43 Metabolome Data by Mass Spectrometry (MS) 168.15 MB raw Controlled
OMIX013654-29 EH7 44 Metabolome Data by Mass Spectrometry (MS) 169.89 MB raw Controlled
OMIX013654-30 EH8 45 Metabolome Data by Mass Spectrometry (MS) 169.92 MB raw Controlled
OMIX013654-33 EH9 46 Metabolome Data by Mass Spectrometry (MS) 168.02 MB raw Controlled
OMIX013654-34 EH10 47 Metabolome Data by Mass Spectrometry (MS) 169.38 MB raw Controlled
OMIX013654-35 BPA1 1 Metabolome Data by Mass Spectrometry (MS) 170.5 MB raw Controlled
OMIX013654-36 BPA2 2 Metabolome Data by Mass Spectrometry (MS) 169.9 MB raw Controlled
OMIX013654-37 BPA3 3 Metabolome Data by Mass Spectrometry (MS) 170.11 MB raw Controlled
OMIX013654-38 BPA5 5 Metabolome Data by Mass Spectrometry (MS) 169.14 MB raw Controlled
OMIX013654-39 BPA4 4 Metabolome Data by Mass Spectrometry (MS) 166.96 MB raw Controlled
OMIX013654-40 BPA6 6 Metabolome Data by Mass Spectrometry (MS) 169.93 MB raw Controlled
OMIX013654-41 BPA7 7 Metabolome Data by Mass Spectrometry (MS) 169.13 MB raw Controlled
OMIX013654-42 BPA9 9 Metabolome Data by Mass Spectrometry (MS) 170.72 MB raw Controlled
OMIX013654-43 BPA8 8 Metabolome Data by Mass Spectrometry (MS) 168.54 MB raw Controlled
OMIX013654-44 BPA11 11 Metabolome Data by Mass Spectrometry (MS) 170.13 MB raw Controlled
OMIX013654-45 BPA10 10 Metabolome Data by Mass Spectrometry (MS) 171.54 MB raw Controlled
OMIX013654-46 BPA13 13 Metabolome Data by Mass Spectrometry (MS) 172.55 MB raw Controlled
OMIX013654-47 BPA12 12 Metabolome Data by Mass Spectrometry (MS) 170.14 MB raw Controlled
OMIX013654-48 BPA15 15 Metabolome Data by Mass Spectrometry (MS) 168.45 MB raw Controlled
OMIX013654-49 BPA14 14 Metabolome Data by Mass Spectrometry (MS) 167.32 MB raw Controlled
OMIX013654-50 EH11 48 Metabolome Data by Mass Spectrometry (MS) 168.92 MB raw Controlled
OMIX013654-51 EH12 49 Metabolome Data by Mass Spectrometry (MS) 170.39 MB raw Controlled
OMIX013654-52 EH16 53 Metabolome Data by Mass Spectrometry (MS) 168.51 MB raw Controlled
OMIX013654-53 EH15 52 Metabolome Data by Mass Spectrometry (MS) 168.55 MB raw Controlled
OMIX013654-54 EH17 54 Metabolome Data by Mass Spectrometry (MS) 168.87 MB raw Controlled
OMIX013654-55 EH18 55 Metabolome Data by Mass Spectrometry (MS) 169.88 MB raw Controlled
OMIX013654-56 EH19 56 Metabolome Data by Mass Spectrometry (MS) 170.69 MB raw Controlled
OMIX013654-57 EH20 57 Metabolome Data by Mass Spectrometry (MS) 171.64 MB raw Controlled
OMIX013654-58 UPA1 58 Metabolome Data by Mass Spectrometry (MS) 173.61 MB raw Controlled
OMIX013654-59 UPA2 59 Metabolome Data by Mass Spectrometry (MS) 170.18 MB raw Controlled
OMIX013654-60 UPA3 60 Metabolome Data by Mass Spectrometry (MS) 171.28 MB raw Controlled
OMIX013654-61 UPA4 61 Metabolome Data by Mass Spectrometry (MS) 175.91 MB raw Controlled
OMIX013654-62 UPA5 62 Metabolome Data by Mass Spectrometry (MS) 173.74 MB raw Controlled
OMIX013654-63 UPA6 63 Metabolome Data by Mass Spectrometry (MS) 173.66 MB raw Controlled
OMIX013654-64 UPA7 64 Metabolome Data by Mass Spectrometry (MS) 170.95 MB raw Controlled
OMIX013654-65 UPA8 65 Metabolome Data by Mass Spectrometry (MS) 174.11 MB raw Controlled
OMIX013654-66 UPA9 66 Metabolome Data by Mass Spectrometry (MS) 170.34 MB raw Controlled
OMIX013654-67 UPA10 67 Metabolome Data by Mass Spectrometry (MS) 169.26 MB raw Controlled
OMIX013654-68 UPA11 68 Metabolome Data by Mass Spectrometry (MS) 169.24 MB raw Controlled
OMIX013654-69 UPA12 69 Metabolome Data by Mass Spectrometry (MS) 171.69 MB raw Controlled
OMIX013654-70 UPA13 70 Metabolome Data by Mass Spectrometry (MS) 169.87 MB raw Controlled
OMIX013654-71 UPA14 71 Metabolome Data by Mass Spectrometry (MS) 169.83 MB raw Controlled
OMIX013654-72 UPA15 72 Metabolome Data by Mass Spectrometry (MS) 172.51 MB raw Controlled
OMIX013654-73 UPA16 73 Metabolome Data by Mass Spectrometry (MS) 169.92 MB raw Controlled
OMIX013654-74 UPA17 74 Metabolome Data by Mass Spectrometry (MS) 167.39 MB raw Controlled
OMIX013654-75 UPA18 75 Metabolome Data by Mass Spectrometry (MS) 170.91 MB raw Controlled
OMIX013654-76 UPA19 76 Metabolome Data by Mass Spectrometry (MS) 171.07 MB raw Controlled
OMIX013654-77 UPA20 77 Metabolome Data by Mass Spectrometry (MS) 172.58 MB raw Controlled
OMIX013654-78 UPA21 78 Metabolome Data by Mass Spectrometry (MS) 170.99 MB raw Controlled
OMIX013654-79 UPA22 79 Metabolome Data by Mass Spectrometry (MS) 171.6 MB raw Controlled
OMIX013654-80 UPA23 80 Metabolome Data by Mass Spectrometry (MS) 175.42 MB raw Controlled
OMIX013654-81 UPA24 81 Metabolome Data by Mass Spectrometry (MS) 170.96 MB raw Controlled
OMIX013654-82 UPA25 82 Metabolome Data by Mass Spectrometry (MS) 171.44 MB raw Controlled
OMIX013654-83 UPA26 83 Metabolome Data by Mass Spectrometry (MS) 172.22 MB raw Controlled
OMIX013654-84 UPA27 84 Metabolome Data by Mass Spectrometry (MS) 171.08 MB raw Controlled
OMIX013654-85 UPA28 85 Metabolome Data by Mass Spectrometry (MS) 168.16 MB raw Controlled
OMIX013654-86 UPA30 87 Metabolome Data by Mass Spectrometry (MS) 173.87 MB raw Controlled
OMIX013654-87 UPA29 86 Metabolome Data by Mass Spectrometry (MS) 167.99 MB raw Controlled
OMIX013654-88 UPA31 88 Metabolome Data by Mass Spectrometry (MS) 174.34 MB raw Controlled
OMIX013654-89 UPA32 89 Metabolome Data by Mass Spectrometry (MS) 171.82 MB raw Controlled
OMIX013654-90 UPA33 90 Metabolome Data by Mass Spectrometry (MS) 173.03 MB raw Controlled
OMIX013654-91 UPA34 91 Metabolome Data by Mass Spectrometry (MS) 171.77 MB raw Controlled
OMIX013654-92 UPA36 93 Metabolome Data by Mass Spectrometry (MS) 172.54 MB raw Controlled
OMIX013654-93 UPA35 92 Metabolome Data by Mass Spectrometry (MS) 170.88 MB raw Controlled
OMIX013654-94 UPA37 94 Metabolome Data by Mass Spectrometry (MS) 172.6 MB raw Controlled
OMIX013654-95 UPA38 95 Metabolome Data by Mass Spectrometry (MS) 170.22 MB raw Controlled
OMIX013654-96 BPA16 16 Metabolome Data by Mass Spectrometry (MS) 168.78 MB raw Controlled
OMIX013654-97 BPA17 17 Metabolome Data by Mass Spectrometry (MS) 171.08 MB raw Controlled
OMIX013654-98 EH13 50 Metabolome Data by Mass Spectrometry (MS) 169.58 MB raw Controlled
OMIX013654-99 EH14 51 Metabolome Data by Mass Spectrometry (MS) 168.88 MB raw Controlled
3Relevant Publications
Paper Title Journal Name Publish Time Accession Citing Type
The role of arachidonic acid metabolites in the subtype classification and pathogenesis of primary aldosteronism iScience 2026-02 OMIX013654 OMIX001234 Deposit

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