| Title | Comparison of the immune microenvironment between lung tumors andbrain metastatic tumors |
|---|---|
| Description | RNA sequencing (RNA-seq) of eighty-six samples from primary lung tumors and paired brain metastases of 43 patients was conducted to analyze the tumor immune microenvironment. |
| Organism | Cancer |
| Data Type | Mixed |
| Data Accessibility | Open-access |
| BioProject | PRJCA006267 |
| Release Date | 2022-05-01 |
| Submitter | Likun Chen (chenlk@sysucc.org.cn) |
| Organization | Sun Yat-sen University Cancer Center |
| Submission Date | 2021-09-10 |
HTTP download speed may be slow. It is highly recommended that you download the dataset using a dedicated FTP tool (such as FileZilla Client).
| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download |
|---|---|---|---|---|---|---|
| OMIX575-20-01 | paired_brainvslung | 86 | Transcriptomic | 57.4 MB | txt |
| Paper Title | Journal Name | Publish Time | Accession | Citing Type |
|---|---|---|---|---|
| Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity | Cell Reports Medicine | 2024-05 | OMIX575 | Secondary use |
| Immune suppressive microenvironment in brain metastatic non-small cell lung cancer: comprehensive immune microenvironment profiling of brain metastases versus paired primary lung tumors (GASTO 1060) | OncoImmunology | 2022-05 | OMIX575 | Deposit |
| An immune scoring system predicts prognosis and immune characteristics in lung adenocarcinoma brain metastases by RNA sequencing | Acta Neuropathologica Communications | 2024-11 | OMIX575 | Secondary use |
| Single-cell and spatial transcriptome landscapes reveal the spatial immune defense pattern shared by primary and brain metastatic lung adenocarcinoma Peer Review File | Journal of Thoracic Disease | 2025-11 | OMIX575 | Secondary use |