OMIX

Epigenetic Impact of Chronic Inflammation On Colon Mucosa Cells

OMIX694

1Summary
Title Epigenetic Impact of Chronic Inflammation On Colon Mucosa Cells
Description To investigate how DNA methylation alterations contribute to inflammation-associated carcinogenesis, chronic colitis mouse model was established by dextran sodium sulfate (DSS) treated and then colon mucosa were separated for Bisulfite genomic sequencing. The methylation level was calculated based on the percentage of methylated cytosine in the whole genome, including mCG, CHG and CHH. Differentially methylated regions (DMRs) both in the upstream, downstream and genebody between DSS-treated colon mucosa (DSS) and control (CK) were identified.
Organism Mus
Data Type -
Data Accessibility Open-access
BioProject PRJCA006765
Release Date 2021-10-11
Submitter Jia He (hejia021@126.com)
Organization The First People’s Hospital of Foshan
Submission Date 2021-10-10
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download Times Download
OMIX694-60-01 Differentially methylated regions in CG (DSS VS. CK) 4 DNA Methylation 1.2 MB rar 0
OMIX694-60-02 Differentially methylated regions in CHG (DSS VS. CK) 4 DNA Methylation 23.7 KB rar 0
OMIX694-60-03 Differentially methylated regions in CHH(DSS VS. CK) 4 DNA Methylation 326.1 KB rar 0

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