OMIX

Elevated testicular apoptosis is associated with elevated sphingosine driven by gut microbiota in prediabetic sheep

OMIX719

1Summary
Title Elevated testicular apoptosis is associated with elevated sphingosine driven by gut microbiota in prediabetic sheep
Description Administration of melatonin alleviates the symptoms of prediabetes, especially those of impaired spermatogenesis, which results from the restoration of gut microbiota and metabolic levels of sphingosine. Our results reveal that sphingosine contributed to the disruption of spermatogenesis and could be a disease marker; furthermore, melatonin represents a potential prebiotic agent for the treatment of male infertility caused by prediabetes and its complications.
Organism Ovis aries
Data Type -
Data Accessibility Open-access
BioProject PRJCA007028
Release Date 2022-05-06
Submitter Shan Liying (1318329288@qq.com)
Organization Inner Mongolia University
Submission Date 2021-11-01
2Files & Download

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File ID File Title Number/Samples File Type File Size File Suffix Download Times Download
OMIX719-30-01 Rescue 10 Metabonomics 789.16 MB mzXML.tar.gz 0
OMIX719-30-02 Prediabetes 10 Metabonomics 833.95 MB mzXML.tar.gz 0
OMIX719-30-03 Control 10 Metabonomics 800.65 MB mzXML.tar.gz 0
OMIX719-30-04 QC 8 Metabonomics 639.23 MB mzXML.tar.gz 0

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