Activity-based protein profilings of compound PAC5
| Title | Activity-based protein profilings of compound PAC5 |
|---|---|
| Description | The strategy of activity-based protein profilings (ABPPs) was used to explore the functional target(s) of PAC5. We synthesized both a positive probe (PAC5-bio, PP) and a negative probe (PAC3-bio, NP) from PAC5 and PAC3 (an inactive analogue of PAC5), respectively, with biotin and an ethylene glycol linker. Then, we performed three independent pull-down experiments using positive and negative probes, respectively. Peptide mass fingerprinting data analysis identified specific proteins in the positive probe pulldowns. |
| Organism | Homo sapiens |
| Data Type | - |
| Data Accessibility | Open-access |
| BioProject | PRJCA007628 |
| Release Date | 2021-12-19 |
| Submitter | shaoxing Dai (daishaoxing@163.com) |
| Organization | Institute of Primate Translational Medicine, Kunming University of Science and Technology |
| Submission Date | 2021-12-19 |
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| File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
|---|---|---|---|---|---|---|---|
| OMIX811-10-01 | F1 | 1 | Proteomic | 236.18 MB | raw | 0 | |
| OMIX811-10-02 | F2 | 1 | Proteomic | 217.18 MB | raw | 0 | |
| OMIX811-10-03 | F3 | 1 | Proteomic | 229.86 MB | raw | 0 | |
| OMIX811-10-04 | F4 | 1 | Proteomic | 231.02 MB | raw | 0 |