Metagenomic Next-Generation Sequencing for the Diagnosis of Neonatal Infectious Diseases
Title | Metagenomic Next-Generation Sequencing for the Diagnosis of Neonatal Infectious Diseases |
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Description | Infections, mainly including sepsis, meningitis, and pneumonia[1, 2], are the primary cause of about 3 million global neonatal deaths per year[1, 3], which contributed more than 20% to the neonatal deaths worldwide[4]. The infected neonates are often treated empirically and unnecessarily[5]. In addition to death, some unoptimistic prognoses may be generated without timely diagnosis and proper therapy, including several neuro-developmental complications[3] and long-term disabilities[6]. Pathogenic profiles are complex, while bacteria, viruses, and fungi are found to be the dominate pathogens[3, 5, 7, 8]. Accordingly, not only timely but accurate identification of pathogens and therapy are needed to decrease the risk of adverse side-effects and improve the prognosis. |
Organism | Streptococcus pneumoniae |
Data Type | - |
Data Accessibility | Open-access |
BioProject | PRJCA008034 |
Release Date | 2022-04-02 |
Submitter | Ye Zhang (zhangye@hugobiotech.com) |
Organization | Hugobiotech Beijing Co.,Ltd. |
Submission Date | 2022-01-20 |
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File ID | File Title | Number/Samples | File Type | File Size | File Suffix | Download Times | Download |
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OMIX898-99-01 | 05.Rename_Reads.tar | 267 | others | 29.92 MB | Rename_Reads.tar.gz | 0 |