| Editing Factor: | ELI1 |
| Synonym: | EDITING LACKING INSERTIONAL MUTANT 1 |
| Description: | The ELI1 DYW deaminase domain was expressed as a recombinant protein in Escherichia coli and was shown to bind two zinc atoms per polypeptide; Thus, the DYW deaminase domain binds a zinc metal ion, as expected for a cytidine deaminase, and is potentially the catalytic component of an editing complex; Genetic complementation experiments demonstrate that large portions of the DYW deaminase domain of ELI1 may be eliminated, but the truncated genes retain the ability to restore editing site conversion in a mutant plant |
| Protein Family: | Pentatricopeptide repeat (PPR) protein |
| Subclass: | DYW |
| Physical Interaction: | NA |
| Construct Structure: | PLS-E-E+-DYW |
| Gene ID & Species: | AT4G37380 (Arabidopsis thaliana) |
| Edited Gene(s): | ndhB |
| Editing Type(s): | C-to-U (6) |
| Publication(s): |
[1] Multiple PPR Protein Interactions Are Involved in the RNA Editing System in Arabidopsis Mitochondria and Plastids, Proc Natl Acad Sci U S A, 2017. [doi:10.1073/pnas.1705815114] [2] Identification of Two Pentatricopeptide Repeat Genes Required for RNA Editing and Zinc Binding by C-terminal Cytidine Deaminase-like Domains, The Journal of Biological Chemistry, 2013. [doi:10.1074/jbc.M113.485755] |
| Species | Gene ID | Organelle | Edited Gene | Position | Region | Nuclear Genome | Organelle Genome | Other Region | Other Position | Editing Type | Codon | Amino Acid | Molecular Effect | Experiment Details | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Arabidopsis thaliana | AT4G37380 | Chloroplast | ndhB | 830 | CDS | NA | NA | NA | NA | C-to-U | UCA=>UUA NA=>NA |
S=>L NA=>NA |
Recoding NA |
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