Introduction

MOTIVATION: MicroRNAs (miRNAs) are short abundant non-coding RNAs critical for many cellular processes. Deep sequencing (next-generation sequencing) technologies are being readily used to receive a more accurate depiction of miRNA expression profiles in living cells. This type of analysis is a key step towards improving our understanding of the complexity and mode of miRNA regulation. RESULTS: miRNAkey is a software package designed to be used as a base-station for the analysis of miRNA deep sequencing data. The package implements common steps taken in the analysis of such data, as well as adds unique features, such as data statistics and multiple read determination, generating a novel platform for the analysis of miRNA expression. A user-friendly graphical interface is applied to determine the analysis steps. The tabular and graphical output contains general and detailed reports on the sequence reads and provides an accurate picture of the differentially expressed miRNAs in paired samples. AVAILABILITY AND IMPLEMENTATION: See http://ibis.tau.ac.il/miRNAkey CONTACT: nshomron@post.tau.ac.il SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Publications

  1. miRNAkey: a software for microRNA deep sequencing analysis.
    Cite this
    Ronen R, Gan I, Modai S, Sukacheov A, Dror G, Halperin E, Shomron N, 2010-10-01 - Bioinformatics (Oxford, England)

Credits

  1. Roy Ronen
    Developer

    Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Israel

  2. Ido Gan
    Developer

  3. Shira Modai
    Developer

  4. Alona Sukacheov
    Developer

  5. Gideon Dror
    Developer

  6. Eran Halperin
    Developer

  7. Noam Shomron
    Investigator

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Summary
AccessionBT000149
Tool TypeApplication
Category
PlatformsLinux/Unix
Technologies
User InterfaceTerminal Command Line
Download Count0
Submitted ByNoam Shomron