Introduction

Large numbers of MS/MS peptide spectra generated in proteomics experiments require efficient, sensitive and specific algorithms for peptide identification. In the Open Mass Spectrometry Search Algorithm (OMSSA), specificity is calculated by a classic probability score using an explicit model for matching experimental spectra to sequences. At default thresholds, OMSSA matches more spectra from a standard protein cocktail than a comparable algorithm. OMSSA is designed to be faster than published algorithms in searching large MS/MS datasets.

Publications

  1. Open mass spectrometry search algorithm.
    Cite this
    Geer LY, Markey SP, Kowalak JA, Wagner L, Xu M, Maynard DM, Yang X, Shi W, Bryant SH, 2004-09-01 - Journal of proteome research

Credits

  1. Lewis Y Geer
    Developer

  2. Sanford P Markey
    Developer

  3. Jeffrey A Kowalak
    Developer

  4. Lukas Wagner
    Developer

  5. Ming Xu
    Developer

  6. Dawn M Maynard
    Developer

  7. Xiaoyu Yang
    Developer

  8. Wenyao Shi
    Developer

  9. Stephen H Bryant
    Investigator

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Summary
AccessionBT000320
Tool TypeApplication
Category
PlatformsLinux/Unix
TechnologiesC++
User InterfaceTerminal Command Line
Download Count0
Submitted ByStephen H Bryant