Introduction

BigWig files are a compressed, indexed, binary format for genome-wide signal data for calculations (e.g. GC percent) or experiments (e.g. ChIP-seq/RNA-seq read depth). bwtool is a tool designed to read bigWig files rapidly and efficiently, providing functionality for extracting data and summarizing it in several ways, globally or at specific regions. Additionally, the tool enables the conversion of the positions of signal data from one genome assembly to another, also known as 'lifting'. We believe bwtool can be useful for the analyst frequently working with bigWig data, which is becoming a standard format to represent functional signals along genomes. The article includes supplementary examples of running the software.The C source code is freely available under the GNU public license v3 at http://cromatina.crg.eu/bwtool.

Publications

  1. bwtool: a tool for bigWig files.
    Cite this
    Pohl A, Beato M, 2014-06-01 - Bioinformatics (Oxford, England)

Credits

  1. Andy Pohl
    Developer

    Department of Gene Regulation, Stem Cells, Spain

  2. Miguel Beato
    Investigator

    Department of Gene Regulation, Stem Cells, Spain

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Summary
AccessionBT000361
Tool TypeApplication
Category
PlatformsLinux/Unix
Technologies
User InterfaceTerminal Command Line
Download Count0
Country/RegionSpain
Submitted ByMiguel Beato