Introduction

The genome-wide study of epigenetic states requires the integrative analysis of histone modification ChIP-seq data. Here, we introduce an easy-to-use analytic framework to compare profiles of enrichment in histone modifications around classes of genomic elements, e.g. transcription start sites (TSS). Our framework is available via the user-friendly R/Bioconductor package DChIPRep. DChIPRep uses biological replicate information as well as chromatin Input data to allow for a rigorous assessment of differential enrichment. DChIPRep is available for download through the Bioconductor project at http://bioconductor.org/packages/DChIPRep. Contact. DChIPRep@gmail.com.

Publications

  1. DChIPRep, an R/Bioconductor package for differential enrichment analysis in chromatin studies.
    Cite this
    Chabbert CD, Steinmetz LM, Klaus B, 2016-01-01 - PeerJ

Credits

  1. Christophe D Chabbert
    Developer

    Genome Biology Unit, European Molecular Biology Laboratory, Germany

  2. Lars M Steinmetz
    Developer

    Genome Biology Unit, European Molecular Biology Laboratory, Germany

  3. Bernd Klaus
    Investigator

    Genome Biology Unit, European Molecular Biology Laboratory, Germany

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Summary
AccessionBT001138
Tool TypeApplication
Category
PlatformsLinux/Unix
TechnologiesR
User InterfaceTerminal Command Line
Download Count0
Country/RegionGermany
Submitted ByBernd Klaus