Introduction

EVidenceModeler (EVM) is presented as an automated eukaryotic gene structure annotation tool that reports eukaryotic gene structures as a weighted consensus of all available evidence. EVM, when combined with the Program to Assemble Spliced Alignments (PASA), yields a comprehensive, configurable annotation system that predicts protein-coding genes and alternatively spliced isoforms. Our experiments on both rice and human genome sequences demonstrate that EVM produces automated gene structure annotation approaching the quality of manual curation.

Publications

  1. Automated eukaryotic gene structure annotation using EVidenceModeler and the Program to Assemble Spliced Alignments.
    Cite this
    Haas BJ, Salzberg SL, Zhu W, Pertea M, Allen JE, Orvis J, White O, Buell CR, Wortman JR, 2008-01-01 - Genome biology

Credits

  1. Brian J Haas
    Developer

    J Craig Venter Institute, The Institute for Genomic Research

  2. Steven L Salzberg
    Developer

  3. Wei Zhu
    Developer

  4. Mihaela Pertea
    Developer

  5. Jonathan E Allen
    Developer

  6. Joshua Orvis
    Developer

  7. Owen White
    Developer

  8. C Robin Buell
    Developer

  9. Jennifer R Wortman
    Investigator

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Summary
AccessionBT001264
Tool TypeApplication
Category
PlatformsLinux/Unix
TechnologiesC++, Perl
User InterfaceTerminal Command Line
Download Count0
Submitted ByJennifer R Wortman