Introduction

We present a significantly improved version of the flowType and RchyOptimyx BioConductor-based pipeline that is both 14 times faster and can accommodate multiple levels of biomarker expression for up to 96 markers. With these improvements, the pipeline is positioned to be an integral part of data analysis for high-throughput experiments on high-dimensional single-cell assay platforms, including flow cytometry, mass cytometry and single-cell RT-qPCR.

Publications

  1. Enhanced flowType/RchyOptimyx: a BioConductor pipeline for discovery in high-dimensional cytometry data.
    Cite this
    O'Neill K, Jalali A, Aghaeepour N, Hoos H, Brinkman RR, 2014-05-01 - Bioinformatics (Oxford, England)
  2. RchyOptimyx: cellular hierarchy optimization for flow cytometry.
    Cite this
    Aghaeepour N, Jalali A, O'Neill K, Chattopadhyay PK, Roederer M, Hoos HH, Brinkman RR, 2012-12-01 - Cytometry. Part A : the journal of the International Society for Analytical Cytology

Credits

  1. Kieran O'Neill
    Developer

    Terry Fox Laboratory, British Columbia Cancer Agency, Canada

  2. Adrin Jalali
    Developer

  3. Nima Aghaeepour
    Developer

  4. Holger Hoos
    Developer

  5. Ryan R Brinkman
    Investigator

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Summary
AccessionBT001831
Tool TypeApplication
Category
PlatformsLinux/Unix
TechnologiesR
User InterfaceTerminal Command Line
Download Count0
Submitted ByRyan R Brinkman